Abstract
The potential biochemical and genetic mechanisms by which a cell might experience a decreased sensitivity to taxanes and other drugs of this class are discussed in the first part of this article. The use of taxanes in the current gynecologic-oncologic clinical setting is reviewed with special consideration given to the pharmacokinetics of taxane in relation to dose intensity and length of administration.
Original language | English (US) |
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Pages (from-to) | 21-41 |
Number of pages | 21 |
Journal | Hematology/Oncology Clinics of North America |
Volume | 13 |
Issue number | 1 |
DOIs | |
State | Published - 1999 |
Externally published | Yes |
ASJC Scopus subject areas
- Hematology
- Oncology