Fungicidal activity of cecropin A

A. J. DeLucca; J. M. Bland; T. J. Jacks; C. Grimm; T. E. Cleveland; T. J. Walsh

doi:10.1128/aac.41.2.481

Fungicidal activity of cecropin A

A. J. DeLucca, J. M. Bland, T. J. Jacks, C. Grimm, T. E. Cleveland, T. J. Walsh

Research output: Contribution to journal › Article › peer-review

90 Scopus citations

Abstract

Cecropin A (CA) fungicidal properties were explored. Nongerminated and germinated Aspergillus spp. and Fusarium spp. conidia were treated with CA. CA achieved complete lethality at ≤25 μM (99 μg/ml) for germinating, but not nongerminating, conidia of Aspergillus spp. CA achieved total lethality for nongerminated and germinating conidia of Fusarium spp at 1.5 μM (6 μg/ml). MIC and minimal lethal concentration assays in buffered RPMI medium gave similar results.

Original language	English (US)
Pages (from-to)	481-483
Number of pages	3
Journal	Antimicrobial agents and chemotherapy
Volume	41
Issue number	2
DOIs	https://doi.org/10.1128/aac.41.2.481
State	Published - 1997
Externally published	Yes

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

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AU - DeLucca, A. J.

AU - Bland, J. M.

AU - Jacks, T. J.

AU - Grimm, C.

AU - Cleveland, T. E.

AU - Walsh, T. J.

PY - 1997

Y1 - 1997

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AB - Cecropin A (CA) fungicidal properties were explored. Nongerminated and germinated Aspergillus spp. and Fusarium spp. conidia were treated with CA. CA achieved complete lethality at ≤25 μM (99 μg/ml) for germinating, but not nongerminating, conidia of Aspergillus spp. CA achieved total lethality for nongerminated and germinating conidia of Fusarium spp at 1.5 μM (6 μg/ml). MIC and minimal lethal concentration assays in buffered RPMI medium gave similar results.

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Fungicidal activity of cecropin A

Abstract

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