Fungicidal activity of cecropin A

A. J. DeLucca, J. M. Bland, T. J. Jacks, C. Grimm, T. E. Cleveland, T. J. Walsh

Research output: Contribution to journalArticlepeer-review


Cecropin A (CA) fungicidal properties were explored. Nongerminated and germinated Aspergillus spp. and Fusarium spp. conidia were treated with CA. CA achieved complete lethality at ≤25 μM (99 μg/ml) for germinating, but not nongerminating, conidia of Aspergillus spp. CA achieved total lethality for nongerminated and germinating conidia of Fusarium spp at 1.5 μM (6 μg/ml). MIC and minimal lethal concentration assays in buffered RPMI medium gave similar results.

Original languageEnglish (US)
Pages (from-to)481-483
Number of pages3
JournalAntimicrobial agents and chemotherapy
Issue number2
StatePublished - 1997

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases

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