Fungal malignant otitis externa: Pitfalls, diagnosis, and treatment

Antoine E. Tarazi, Jaffar A. Al-Tawfiq, Rifat F. Abdi

Research output: Contribution to journalReview articlepeer-review

Abstract

Hypothesis: Oral voriconazole is a viable alternative modality treatment to traditionally used intravenous vancomycin in the treatment of malignant otitis externa (MOE). Background: The incidence of MOE is on the rise, more so in Saudi Arabia where diabetes mellitus is endemic. Although Pseudomonas aeruginosa is the most common offending organism, we are observing an increasing number of fungal MOE, in particular, Aspergillus species. The clinical findings in these patients can be quite different from those of the classic gram-negative bacteria. Methods: Chart review of patients with a diagnosis of MOE who underwent oral voriconazole treatment. Results: Three cases of Aspergillus MOE are reported in detail, pointing the pitfalls in clinical findings, diagnosis, and management of this entity. Conclusion: Oral voriconazole proved to be an excellent alternative modality treatment in this population of patients with MOE.

Original languageEnglish (US)
Pages (from-to)769-773
Number of pages5
JournalOtology and Neurotology
Volume33
Issue number5
DOIs
StatePublished - Jul 1 2012
Externally publishedYes

Keywords

  • Aspergillus
  • Malignant otitis externa
  • Voriconazole

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Sensory Systems
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Fungal malignant otitis externa: Pitfalls, diagnosis, and treatment'. Together they form a unique fingerprint.

Cite this