Fungal DNA detected in blood samples of patients who received contaminated methylprednisolone injections reveals increased complexity of causative agents

Yanan Zhao, Emilian Armeanu, Richard DiVerniero, Terri A. Lewis, Richard C. Dobson, Dimitrios P. Kontoyiannis, Emmanuel Roilides, Thomas J. Walsh, David S. Perlina

Research output: Contribution to journalArticle

Abstract

Using Exserohilum rostratum-specific and panfungal real-time PCR, we studied 24 blood samples and 2 synovial fluid specimens from 20 patients with persistent or worsening pain following injections of contaminated methylprednisolone. Seven blood specimens from 6 patients were significantly positive for fungal DNA by panfungal PCR, with multiple fungal species identified.

Original languageEnglish (US)
Pages (from-to)2212-2215
Number of pages4
JournalJournal of clinical microbiology
Volume52
Issue number6
DOIs
StatePublished - Jun 2014

ASJC Scopus subject areas

  • Microbiology (medical)

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    Zhao, Y., Armeanu, E., DiVerniero, R., Lewis, T. A., Dobson, R. C., Kontoyiannis, D. P., Roilides, E., Walsh, T. J., & Perlina, D. S. (2014). Fungal DNA detected in blood samples of patients who received contaminated methylprednisolone injections reveals increased complexity of causative agents. Journal of clinical microbiology, 52(6), 2212-2215. https://doi.org/10.1128/JCM.00854-14