Fungal brain infections

Eileen P. Scully, Lindsey R. Baden, Joel T. Katz

Research output: Contribution to journalReview articlepeer-review

Abstract

PURPOSE OF REVIEW: Fungal infections of the central nervous system, once a relatively rare occurrence, are increasingly common due to the expansion of immunocompromised populations at risk, and therefore are important to recognize early and manage appropriately. RECENT FINDINGS: The specific infectious risk posed by novel immune-modifying therapies can, in most cases, be predicted on the basis of the immune target and medication timing. In addition, major advances in noninvasive diagnostic tests (e.g. serum beta glucan and galactomannan assays), and the recent introduction of more effective antifungal therapies, have led to a dramatic improvement in clinical outcomes. SUMMARY: The current review provides approaches to patients with suspected central nervous system fungal infections based on host-risk factors, clinical syndromes and specific pathogens.

Original languageEnglish (US)
Pages (from-to)347-352
Number of pages6
JournalCurrent opinion in neurology
Volume21
Issue number3
DOIs
StatePublished - Jun 1 2008
Externally publishedYes

Keywords

  • Aspergillus
  • Candida
  • Central nervous system
  • Fungi
  • Mycoses

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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