Functional volumetric MRI in assessing treatment response to intra-arterial therapy of primary and secondary liver tumors

Research output: Contribution to journalArticle

Abstract

The assessment of tumor response after intra-arterial therapy (IAT) is useful to determine treatment success, to guide future treatments, and to predict patient outcome. Changes in tumor size in the axial plane after transarterial therapies might be delayed with the traditional criteria, whereas cellular tumor changes can be detected earlier by functional metrics such as vascular enhancement and cellular integrity in the entire tumor volume. Magnetic resonance imaging has become an important tool in the evaluation of early tumor response with the introduction of new techniques, such as diffusion-weighted imaging and apparent diffusion coefficient maps, and the development of advanced software to quantify vascular enhancement after IATs. This review discusses the role of treatment response by functional volumetric imaging after IAT in patients with primary and secondary liver tumors.

Original languageEnglish (US)
Pages (from-to)513-517
Number of pages5
JournalJournal of Computer Assisted Tomography
Volume38
Issue number4
DOIs
StatePublished - 2014

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Magnetic Resonance Imaging
Liver
Neoplasms
Blood Vessels
Therapeutics
Tumor Burden
Software

Keywords

  • functional volumetric MRI
  • intra-arterial therapy
  • liver tumors
  • treatment response

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

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abstract = "The assessment of tumor response after intra-arterial therapy (IAT) is useful to determine treatment success, to guide future treatments, and to predict patient outcome. Changes in tumor size in the axial plane after transarterial therapies might be delayed with the traditional criteria, whereas cellular tumor changes can be detected earlier by functional metrics such as vascular enhancement and cellular integrity in the entire tumor volume. Magnetic resonance imaging has become an important tool in the evaluation of early tumor response with the introduction of new techniques, such as diffusion-weighted imaging and apparent diffusion coefficient maps, and the development of advanced software to quantify vascular enhancement after IATs. This review discusses the role of treatment response by functional volumetric imaging after IAT in patients with primary and secondary liver tumors.",
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