TY - JOUR
T1 - Functional Outcomes of Anemia in Older Adults
AU - Chaves, Paulo H.M.
PY - 2008/10
Y1 - 2008/10
N2 - Observational studies have consistently documented independent, strong associations of anemia-even if not severe-with major adverse functional outcomes in older adults. In this chapter, recent epidemiologic evidence linking mild anemia with decline in physical and cognitive function, frailty, and disability in community-dwelling older adults is reviewed. Altogether, these biologically plausible associations provide empirical, though not conclusive, support for the notion of mild anemia as a cause of adverse functional outcomes in older adults. Randomized clinical trial data assessing the impact of anemia correction on functional outcomes are lacking at this time.
AB - Observational studies have consistently documented independent, strong associations of anemia-even if not severe-with major adverse functional outcomes in older adults. In this chapter, recent epidemiologic evidence linking mild anemia with decline in physical and cognitive function, frailty, and disability in community-dwelling older adults is reviewed. Altogether, these biologically plausible associations provide empirical, though not conclusive, support for the notion of mild anemia as a cause of adverse functional outcomes in older adults. Randomized clinical trial data assessing the impact of anemia correction on functional outcomes are lacking at this time.
UR - http://www.scopus.com/inward/record.url?scp=52249114922&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=52249114922&partnerID=8YFLogxK
U2 - 10.1053/j.seminhematol.2008.06.005
DO - 10.1053/j.seminhematol.2008.06.005
M3 - Article
C2 - 18809096
AN - SCOPUS:52249114922
SN - 0037-1963
VL - 45
SP - 255
EP - 260
JO - Seminars in Hematology
JF - Seminars in Hematology
IS - 4
ER -