Functional impairment, disability, and frailty in adults aging with HIV-infection

Kristine M. Erlandson, Jennifer A Schrack, Catherine M. Jankowski, Todd T Brown, Thomas B. Campbell

Research output: Contribution to journalArticle

Abstract

The integration of antiretroviral therapy (i.e., ART) into HIV care has dramatically extended the life expectancy of those living with HIV. However, in comparison to similar HIV-uninfected populations, HIV-infected persons experience an excess of morbidity and mortality with an early onset of aging complications including neurocognitive decline, osteoporosis, impaired physical function, frailty, and falls. Recent consensus guidelines encourage clinicians and researchers to consider functional impairment of HIV-infected adults as a measure to understand the impact of aging across a range of abilities. Despite the importance of assessing function in persons aging with HIV infection, a lack of consistent terminology and standardization of assessment tools has limited the application of functional assessments in clinical or research settings. Herein, we distinguish between different approaches used to assess function, describe what is known about function in the aging HIV population, and consider directions for future research.

Original languageEnglish (US)
Pages (from-to)279-290
Number of pages12
JournalCurrent HIV/AIDS Reports
Volume11
Issue number3
DOIs
StatePublished - Sep 1 2014
Externally publishedYes

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HIV Infections
HIV
Life Expectancy
Terminology
Population
Osteoporosis
Research Personnel
Guidelines
Morbidity
Mortality
Research

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Functional impairment, disability, and frailty in adults aging with HIV-infection. / Erlandson, Kristine M.; Schrack, Jennifer A; Jankowski, Catherine M.; Brown, Todd T; Campbell, Thomas B.

In: Current HIV/AIDS Reports, Vol. 11, No. 3, 01.09.2014, p. 279-290.

Research output: Contribution to journalArticle

Erlandson, Kristine M. ; Schrack, Jennifer A ; Jankowski, Catherine M. ; Brown, Todd T ; Campbell, Thomas B. / Functional impairment, disability, and frailty in adults aging with HIV-infection. In: Current HIV/AIDS Reports. 2014 ; Vol. 11, No. 3. pp. 279-290.
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