Functional imaging of the vascular bed by dynamic optical tomography

Randall L. Barbour, Harry L. Graber, Yaling Pei, Christoph H. Schmitz, Yong Xu, Adriana Di Martino, F. Xavier Castellanos, David P. Klemer, Rosemarie E. Hardin, Nelson A. Franco, Michael S. Katz, Michael E. Zenilman, Alessandro G. Smeraldi, Thomas F. Panetta

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this report we present a brief outline of our technological approaches to developing a comprehensive imaging platform suitable for the investigation of the dynamics of the hemoglobin signal in large tissue structures using NIRS imaging techniques. Our approach includes a combined hardware and software development effort that provides for i) hardware integration, ii) system calibration, iii) data integrity checks, iv) image recovery, v) image enhancement and vi) signal processing. Presented are representative results obtained from human subjects that explore the sensitivity and other capabilities of the measuring system to detect focal hemodynamic responses in the head, breast and limb of volunteers. Results obtained support the contention that time-series NIRS imaging is a powerful and sensitive technique for exploring the hemodynamics of healthy and diseased tissues.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsA.A. Amini, A. Mandura
Pages132-149
Number of pages18
Volume5369
DOIs
StatePublished - 2004
Externally publishedYes
EventMedical Imaging 2004: Physiology, Function, and Structure from Medical Images - San Diego, CA, United States
Duration: Feb 15 2004Feb 17 2004

Other

OtherMedical Imaging 2004: Physiology, Function, and Structure from Medical Images
CountryUnited States
CitySan Diego, CA
Period2/15/042/17/04

Fingerprint

Optical tomography
beds
hardware
tomography
hemodynamic responses
Hemodynamics
Imaging techniques
systems integration
Computer hardware
hemodynamics
image enhancement
hemoglobin
limbs
imaging techniques
breast
integrity
Tissue
signal processing
platforms
Image enhancement

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Barbour, R. L., Graber, H. L., Pei, Y., Schmitz, C. H., Xu, Y., Di Martino, A., ... Panetta, T. F. (2004). Functional imaging of the vascular bed by dynamic optical tomography. In A. A. Amini, & A. Mandura (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 5369, pp. 132-149) https://doi.org/10.1117/12.537957

Functional imaging of the vascular bed by dynamic optical tomography. / Barbour, Randall L.; Graber, Harry L.; Pei, Yaling; Schmitz, Christoph H.; Xu, Yong; Di Martino, Adriana; Castellanos, F. Xavier; Klemer, David P.; Hardin, Rosemarie E.; Franco, Nelson A.; Katz, Michael S.; Zenilman, Michael E.; Smeraldi, Alessandro G.; Panetta, Thomas F.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / A.A. Amini; A. Mandura. Vol. 5369 2004. p. 132-149.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Barbour, RL, Graber, HL, Pei, Y, Schmitz, CH, Xu, Y, Di Martino, A, Castellanos, FX, Klemer, DP, Hardin, RE, Franco, NA, Katz, MS, Zenilman, ME, Smeraldi, AG & Panetta, TF 2004, Functional imaging of the vascular bed by dynamic optical tomography. in AA Amini & A Mandura (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 5369, pp. 132-149, Medical Imaging 2004: Physiology, Function, and Structure from Medical Images, San Diego, CA, United States, 2/15/04. https://doi.org/10.1117/12.537957
Barbour RL, Graber HL, Pei Y, Schmitz CH, Xu Y, Di Martino A et al. Functional imaging of the vascular bed by dynamic optical tomography. In Amini AA, Mandura A, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 5369. 2004. p. 132-149 https://doi.org/10.1117/12.537957
Barbour, Randall L. ; Graber, Harry L. ; Pei, Yaling ; Schmitz, Christoph H. ; Xu, Yong ; Di Martino, Adriana ; Castellanos, F. Xavier ; Klemer, David P. ; Hardin, Rosemarie E. ; Franco, Nelson A. ; Katz, Michael S. ; Zenilman, Michael E. ; Smeraldi, Alessandro G. ; Panetta, Thomas F. / Functional imaging of the vascular bed by dynamic optical tomography. Proceedings of SPIE - The International Society for Optical Engineering. editor / A.A. Amini ; A. Mandura. Vol. 5369 2004. pp. 132-149
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