TY - GEN
T1 - Functional classification of schizophrenia using feed forward neural networks
AU - Jafri, Madiha J.
AU - Calhoun, Vince D.
PY - 2006
Y1 - 2006
N2 - In medicine, the nature of an illness is often determined through behavioral or biological markers. The process of diagnosis becomes difficult when dealing with mental disorders since they rely primarily on behavioral markers. Schizophrenia is an example of a complex mental disorder that relies on aberrant behavior such as auditory hallucinations, dampening of emotions, paranoia, etc. This research is an attempt to determine a biological marker for schizophrenia through the use of functional magnetic resonance imaging (fMRI). In this paper, we propose a method of classification of schizophrenia and healthy controls, using a neural network approach and functional brain 'modes' estimated from resting state data using independent component analysis. A reliable technique for discriminating schizophrenia based upon fMRI would be a significant advance and may also provide additional information about the biological implications of mental illness.
AB - In medicine, the nature of an illness is often determined through behavioral or biological markers. The process of diagnosis becomes difficult when dealing with mental disorders since they rely primarily on behavioral markers. Schizophrenia is an example of a complex mental disorder that relies on aberrant behavior such as auditory hallucinations, dampening of emotions, paranoia, etc. This research is an attempt to determine a biological marker for schizophrenia through the use of functional magnetic resonance imaging (fMRI). In this paper, we propose a method of classification of schizophrenia and healthy controls, using a neural network approach and functional brain 'modes' estimated from resting state data using independent component analysis. A reliable technique for discriminating schizophrenia based upon fMRI would be a significant advance and may also provide additional information about the biological implications of mental illness.
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U2 - 10.1109/IEMBS.2006.260906
DO - 10.1109/IEMBS.2006.260906
M3 - Conference contribution
C2 - 17959471
AN - SCOPUS:34047152331
SN - 1424400325
SN - 9781424400324
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SP - 6631
EP - 6634
BT - 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
T2 - 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
Y2 - 30 August 2006 through 3 September 2006
ER -