From spindle checkpoint to cancer

Christoph Lengauer, Zhenghe Wang

Research output: Contribution to journalArticlepeer-review

Abstract

Truncating and missense mutations in BUB1B, encoding the mitotic spindle checkpoint protein BUBR1, have been identified in individuals with mosaic variegated aneuploidy. This finding supports the idea that there is a genetic basis for aneuploidy in cancers.

Original languageEnglish (US)
Pages (from-to)1144-1145
Number of pages2
JournalNature Genetics
Volume36
Issue number11
DOIs
StatePublished - Nov 2004

ASJC Scopus subject areas

  • Genetics(clinical)
  • Genetics

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