From spindle checkpoint to cancer

Christoph Lengauer; Zhenghe Wang

doi:10.1038/ng1104-1144

From spindle checkpoint to cancer

Christoph Lengauer, Zhenghe Wang

School of Medicine

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Truncating and missense mutations in BUB1B, encoding the mitotic spindle checkpoint protein BUBR1, have been identified in individuals with mosaic variegated aneuploidy. This finding supports the idea that there is a genetic basis for aneuploidy in cancers.

Original language	English (US)
Pages (from-to)	1144-1145
Number of pages	2
Journal	Nature Genetics
Volume	36
Issue number	11
DOIs	https://doi.org/10.1038/ng1104-1144
State	Published - Nov 2004

ASJC Scopus subject areas

Genetics(clinical)
Genetics

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10.1038/ng1104-1144

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title = "From spindle checkpoint to cancer",

abstract = "Truncating and missense mutations in BUB1B, encoding the mitotic spindle checkpoint protein BUBR1, have been identified in individuals with mosaic variegated aneuploidy. This finding supports the idea that there is a genetic basis for aneuploidy in cancers.",

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From spindle checkpoint to cancer

Abstract

ASJC Scopus subject areas

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