From molecules to man: The dawn of a vitreous man

Michel Modo, Jeff W.M. Bulte

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

One of the greatest challenges to study the structure, function, and molecules in the living brain is that it is enclosed within the skull and difficult to access. Although biopsies are feasible, they are invasive, could lead to functional impairments, and in any case will only provide a small regional sample that is not necessarily reflecting the entire brain. Since the beginning of the twentieth century, in vivo imaging has gradually, and steadily, matured into non-invasive techniques that enable the repeated investigation of the structural, functional, cellular, and molecular composition of the brain. Not only is this information of great importance to scientists aiming to understand how the brain works, but these techniques are also essential to physicians who use imaging to diagnose and treat disease. The current book is a collection of 29 cutting-edge methods and protocols that are used in the current field of neuroimaging.

Original languageEnglish (US)
Title of host publicationMagnetic Resonance Neuroimaging
Subtitle of host publicationMethods and Protocols
EditorsMichel Modo, Jelte Bulte
Pages3-14
Number of pages12
DOIs
StatePublished - Dec 1 2010

Publication series

NameMethods in Molecular Biology
Volume711
ISSN (Print)1064-3745

Keywords

  • Neuroimaging
  • computer tomography
  • magnetic resonance imaging
  • positron emission tomography

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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