FRET-based activity biosensors to probe compartmentalized signaling

Xinxin Gao, Jin Zhang

Research output: Contribution to journalArticlepeer-review


Illuminating compartmentalized signaling: We discuss the applications of FRET-based biosensors with a focus on understanding compartmentalized signaling of kinase and second-messenger dynamics. With their unique features of genetic encodability and targetability, these biosensors allow real-time tracking of activity dynamics with high spatiotemporal resolution. (Figure Presented).

Original languageEnglish (US)
Pages (from-to)147-151
Number of pages5
Issue number2
StatePublished - Jan 25 2010


  • Biosensors
  • FRET
  • Kinases
  • Second messenger
  • Signaling compartmentation

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Molecular Medicine
  • Molecular Biology

Fingerprint Dive into the research topics of 'FRET-based activity biosensors to probe compartmentalized signaling'. Together they form a unique fingerprint.

Cite this