Frequent low doses of intravenous mechlorethamine for late stage mycosis fungoides lymphoma

E. J. van Scott; D. A. Grekin; J. D. Kalmanson; E. C. Vonderheid; W. E. Barry

doi:10.1002/1097-0142(197511)36:5<1613::AID-CNCR2820360513>3.0.CO;2-0

Frequent low doses of intravenous mechlorethamine for late stage mycosis fungoides lymphoma

E. J. van Scott, D. A. Grekin, J. D. Kalmanson, E. C. Vonderheid, W. E. Barry

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Ninety two courses of daily low dose intravenous nitrogen mustard were administered to 46 patients with advanced cutaneous lymphomas (mycosis fungoides, Sezary syndrome and lymphoma cutis). Seventy eight per cent of patients showed objective clinical remission, and 35% reached a clinically disease free state following 1 or more courses. The response rate was greater in patients with the plaque tumor type of mycosis fungoides than in those with erythrodermic variants. Therapy was free of significant side effects.

Original language	English (US)
Pages (from-to)	1613-1618
Number of pages	6
Journal	Cancer
Volume	36
Issue number	5
DOIs	https://doi.org/10.1002/1097-0142(197511)36:5<1613::AID-CNCR2820360513>3.0.CO;2-0
State	Published - 1975
Externally published	Yes

ASJC Scopus subject areas

Cancer Research
Oncology

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10.1002/1097-0142(197511)36:5<1613::AID-CNCR2820360513>3.0.CO;2-0

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title = "Frequent low doses of intravenous mechlorethamine for late stage mycosis fungoides lymphoma",

abstract = "Ninety two courses of daily low dose intravenous nitrogen mustard were administered to 46 patients with advanced cutaneous lymphomas (mycosis fungoides, Sezary syndrome and lymphoma cutis). Seventy eight per cent of patients showed objective clinical remission, and 35% reached a clinically disease free state following 1 or more courses. The response rate was greater in patients with the plaque tumor type of mycosis fungoides than in those with erythrodermic variants. Therapy was free of significant side effects.",

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year = "1975",

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T1 - Frequent low doses of intravenous mechlorethamine for late stage mycosis fungoides lymphoma

AU - van Scott, E. J.

AU - Grekin, D. A.

AU - Kalmanson, J. D.

AU - Vonderheid, E. C.

AU - Barry, W. E.

PY - 1975

Y1 - 1975

N2 - Ninety two courses of daily low dose intravenous nitrogen mustard were administered to 46 patients with advanced cutaneous lymphomas (mycosis fungoides, Sezary syndrome and lymphoma cutis). Seventy eight per cent of patients showed objective clinical remission, and 35% reached a clinically disease free state following 1 or more courses. The response rate was greater in patients with the plaque tumor type of mycosis fungoides than in those with erythrodermic variants. Therapy was free of significant side effects.

AB - Ninety two courses of daily low dose intravenous nitrogen mustard were administered to 46 patients with advanced cutaneous lymphomas (mycosis fungoides, Sezary syndrome and lymphoma cutis). Seventy eight per cent of patients showed objective clinical remission, and 35% reached a clinically disease free state following 1 or more courses. The response rate was greater in patients with the plaque tumor type of mycosis fungoides than in those with erythrodermic variants. Therapy was free of significant side effects.

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JO - Cancer

JF - Cancer

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ER -

Frequent low doses of intravenous mechlorethamine for late stage mycosis fungoides lymphoma

Abstract

ASJC Scopus subject areas

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