Frequency of sample submission for optimal utilization of the cell culture cytotoxicity assay for detection of Clostridium difficile toxin

Anita P. Borek, Deborah Z. Aird, Karen C Carroll

Research output: Contribution to journalArticle

Abstract

We reviewed the results of repeated sample submissions within a 7-day time frame for Clostridium difficile toxin testing. A total of 2,940 samples were tested during a 3-month period using a cell culture cytotoxicity assay (CCCA). The results from all second samples (n = 1,101) were concordant with the original test result. In only two cases (0.8%; n = 247) was a third sample positive when the first two samples were negative. In this study, submission of multiple samples for CCCA did not increase detection of Clostridium difficile infection.

Original languageEnglish (US)
Pages (from-to)2994-2995
Number of pages2
JournalJournal of Clinical Microbiology
Volume43
Issue number6
DOIs
StatePublished - Jun 2005

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Clostridium difficile
Cell Culture Techniques
Clostridium Infections

ASJC Scopus subject areas

  • Microbiology (medical)
  • Microbiology

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Frequency of sample submission for optimal utilization of the cell culture cytotoxicity assay for detection of Clostridium difficile toxin. / Borek, Anita P.; Aird, Deborah Z.; Carroll, Karen C.

In: Journal of Clinical Microbiology, Vol. 43, No. 6, 06.2005, p. 2994-2995.

Research output: Contribution to journalArticle

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