Frequency dependence of MR relaxation times. II. Iron oxides.

Jeff W Bulte, J. Vymazal, R. A. Brooks, C. Pierpaoli, J. A. Frank

Research output: Contribution to journalArticle

Abstract

The frequency dependence of T1 and T2 was measured for homogeneous suspensions of magnetite and iron oxyhydroxide particles in water with various concentrations of gelatin. The transverse relaxivity showed two types of behavior: (a) For magnetic particles, there was a rapid increase in T2 relaxivity with frequency, followed by a saturation plateau, which accorded with the Langevin magnetization function. From these curves, the magnetic moment of the particle domains was estimated to range from 0.8 to 6.3 x 10(4) Bohr magnetons. (b) For iron oxyhydroxide (ferritin, ferrihydrite, and akaganéite) particles, T2 relaxivity increased linearly with frequency, the slope of the increase characteristic for each particle. T2 relaxivity generally increased with increasing gelatin concentration, corresponding to the measured decrease in the water diffusion coefficient. For iron oxides, homogeneously distributed either as iatrogenic agents or endogenous biominerals, these findings may aid in the interpretation of in vivo relaxivity and the effect on MR imaging.

Original languageEnglish (US)
Pages (from-to)641-648
Number of pages8
JournalJournal of Magnetic Resonance Imaging
Volume3
Issue number4
StatePublished - Jul 1993
Externally publishedYes

Fingerprint

Gelatin
Ferrosoferric Oxide
Water
Ferritins
Suspensions
ferric oxide
ferric hydroxide
ferrihydrite

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Bulte, J. W., Vymazal, J., Brooks, R. A., Pierpaoli, C., & Frank, J. A. (1993). Frequency dependence of MR relaxation times. II. Iron oxides. Journal of Magnetic Resonance Imaging, 3(4), 641-648.

Frequency dependence of MR relaxation times. II. Iron oxides. / Bulte, Jeff W; Vymazal, J.; Brooks, R. A.; Pierpaoli, C.; Frank, J. A.

In: Journal of Magnetic Resonance Imaging, Vol. 3, No. 4, 07.1993, p. 641-648.

Research output: Contribution to journalArticle

Bulte, JW, Vymazal, J, Brooks, RA, Pierpaoli, C & Frank, JA 1993, 'Frequency dependence of MR relaxation times. II. Iron oxides.', Journal of Magnetic Resonance Imaging, vol. 3, no. 4, pp. 641-648.
Bulte JW, Vymazal J, Brooks RA, Pierpaoli C, Frank JA. Frequency dependence of MR relaxation times. II. Iron oxides. Journal of Magnetic Resonance Imaging. 1993 Jul;3(4):641-648.
Bulte, Jeff W ; Vymazal, J. ; Brooks, R. A. ; Pierpaoli, C. ; Frank, J. A. / Frequency dependence of MR relaxation times. II. Iron oxides. In: Journal of Magnetic Resonance Imaging. 1993 ; Vol. 3, No. 4. pp. 641-648.
@article{59284dc9eb004f3c9f9b30d9ec565881,
title = "Frequency dependence of MR relaxation times. II. Iron oxides.",
abstract = "The frequency dependence of T1 and T2 was measured for homogeneous suspensions of magnetite and iron oxyhydroxide particles in water with various concentrations of gelatin. The transverse relaxivity showed two types of behavior: (a) For magnetic particles, there was a rapid increase in T2 relaxivity with frequency, followed by a saturation plateau, which accorded with the Langevin magnetization function. From these curves, the magnetic moment of the particle domains was estimated to range from 0.8 to 6.3 x 10(4) Bohr magnetons. (b) For iron oxyhydroxide (ferritin, ferrihydrite, and akagan{\'e}ite) particles, T2 relaxivity increased linearly with frequency, the slope of the increase characteristic for each particle. T2 relaxivity generally increased with increasing gelatin concentration, corresponding to the measured decrease in the water diffusion coefficient. For iron oxides, homogeneously distributed either as iatrogenic agents or endogenous biominerals, these findings may aid in the interpretation of in vivo relaxivity and the effect on MR imaging.",
author = "Bulte, {Jeff W} and J. Vymazal and Brooks, {R. A.} and C. Pierpaoli and Frank, {J. A.}",
year = "1993",
month = "7",
language = "English (US)",
volume = "3",
pages = "641--648",
journal = "Journal of Magnetic Resonance Imaging",
issn = "1053-1807",
publisher = "John Wiley and Sons Inc.",
number = "4",

}

TY - JOUR

T1 - Frequency dependence of MR relaxation times. II. Iron oxides.

AU - Bulte, Jeff W

AU - Vymazal, J.

AU - Brooks, R. A.

AU - Pierpaoli, C.

AU - Frank, J. A.

PY - 1993/7

Y1 - 1993/7

N2 - The frequency dependence of T1 and T2 was measured for homogeneous suspensions of magnetite and iron oxyhydroxide particles in water with various concentrations of gelatin. The transverse relaxivity showed two types of behavior: (a) For magnetic particles, there was a rapid increase in T2 relaxivity with frequency, followed by a saturation plateau, which accorded with the Langevin magnetization function. From these curves, the magnetic moment of the particle domains was estimated to range from 0.8 to 6.3 x 10(4) Bohr magnetons. (b) For iron oxyhydroxide (ferritin, ferrihydrite, and akaganéite) particles, T2 relaxivity increased linearly with frequency, the slope of the increase characteristic for each particle. T2 relaxivity generally increased with increasing gelatin concentration, corresponding to the measured decrease in the water diffusion coefficient. For iron oxides, homogeneously distributed either as iatrogenic agents or endogenous biominerals, these findings may aid in the interpretation of in vivo relaxivity and the effect on MR imaging.

AB - The frequency dependence of T1 and T2 was measured for homogeneous suspensions of magnetite and iron oxyhydroxide particles in water with various concentrations of gelatin. The transverse relaxivity showed two types of behavior: (a) For magnetic particles, there was a rapid increase in T2 relaxivity with frequency, followed by a saturation plateau, which accorded with the Langevin magnetization function. From these curves, the magnetic moment of the particle domains was estimated to range from 0.8 to 6.3 x 10(4) Bohr magnetons. (b) For iron oxyhydroxide (ferritin, ferrihydrite, and akaganéite) particles, T2 relaxivity increased linearly with frequency, the slope of the increase characteristic for each particle. T2 relaxivity generally increased with increasing gelatin concentration, corresponding to the measured decrease in the water diffusion coefficient. For iron oxides, homogeneously distributed either as iatrogenic agents or endogenous biominerals, these findings may aid in the interpretation of in vivo relaxivity and the effect on MR imaging.

UR - http://www.scopus.com/inward/record.url?scp=0027630213&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027630213&partnerID=8YFLogxK

M3 - Article

C2 - 8347958

AN - SCOPUS:0027630213

VL - 3

SP - 641

EP - 648

JO - Journal of Magnetic Resonance Imaging

JF - Journal of Magnetic Resonance Imaging

SN - 1053-1807

IS - 4

ER -