Free-breathing, nongated real-time delayed enhancement MRI of myocardial infarcts: A comparison with conventional delayed enhancement

Jay S. Detsky, John J. Graham, Ram Vijayaraghavan, Labonny Biswas, Jeffrey A. Stainsby, Michael A. Guttman, Graham A. Wright, Alexander J. Dick

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To compare a free-breathing, nongated, and black-blood real-time delayed enhancement (RT-DE) sequence to the conventional inversion recovery gradient echo (IR-GRE) sequence for delayed enhancement MRI. Materials and Methods: Twenty-three patients with suspected myocardial infarct (MI) were examined using both the IR-GRE and RT-DE imaging sequences. The sensitivity and specificity of RT-DE for detecting MI, using IR-GRE as the gold standard, was determined. The contrast-to-noise ratios (CNR) between the two techniques were also compared. Results: RT-DE had a high sensitivity and specificity (94% and 98%, respectively) for identifying MI. The total acquisition time to image the entire left ventricle was significantly shorter using RT-DE than IR-GRE (5.6 ± 0.9 versus 11.5 ± 1.9 min). RT-DE had a slightly lower infarct-myocardium CNR but a higher infarct-blood CNR than IR-GRE imaging. Compared with IR-GRE, RT-DE accurately measured total infarct sizes. Conclusion: RT-DE can be used for delayed enhancement imaging during free-breathing and without cardiac gating.

Original languageEnglish (US)
Pages (from-to)621-625
Number of pages5
JournalJournal of Magnetic Resonance Imaging
Volume28
Issue number3
DOIs
StatePublished - Sep 2008

Keywords

  • Delayed enhancement
  • MRI
  • Myocardial infarct
  • Real-time
  • SSFP

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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