Fragile site in chromosome 12 in a patient with two miscarriages

G. Stetten; B. Sroka; M. Norbury-Glaser; V. L. Corson

doi:10.1002/ajmg.1320310306

Fragile site in chromosome 12 in a patient with two miscarriages

G. Stetten, B. Sroka, M. Norbury-Glaser, V. L. Corson

School of Medicine

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

A heritable fragile site at 12q13 is described in lymphocytes from a woman with a history of multiple miscarriage. The fragile site was not typically folate-sensitive, being expressed in standard medium. The presence of this fragile site may have led to meiotic chromosome breakage and consequent infertility.

Original language	English (US)
Pages (from-to)	521-525
Number of pages	5
Journal	American journal of medical genetics
Volume	31
Issue number	3
DOIs	https://doi.org/10.1002/ajmg.1320310306
State	Published - 1988

ASJC Scopus subject areas

Genetics(clinical)

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10.1002/ajmg.1320310306

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title = "Fragile site in chromosome 12 in a patient with two miscarriages",

abstract = "A heritable fragile site at 12q13 is described in lymphocytes from a woman with a history of multiple miscarriage. The fragile site was not typically folate-sensitive, being expressed in standard medium. The presence of this fragile site may have led to meiotic chromosome breakage and consequent infertility.",

author = "G. Stetten and B. Sroka and M. Norbury-Glaser and Corson, {V. L.}",

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AU - Stetten, G.

AU - Sroka, B.

AU - Norbury-Glaser, M.

AU - Corson, V. L.

PY - 1988

Y1 - 1988

N2 - A heritable fragile site at 12q13 is described in lymphocytes from a woman with a history of multiple miscarriage. The fragile site was not typically folate-sensitive, being expressed in standard medium. The presence of this fragile site may have led to meiotic chromosome breakage and consequent infertility.

AB - A heritable fragile site at 12q13 is described in lymphocytes from a woman with a history of multiple miscarriage. The fragile site was not typically folate-sensitive, being expressed in standard medium. The presence of this fragile site may have led to meiotic chromosome breakage and consequent infertility.

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JO - American journal of medical genetics

JF - American journal of medical genetics

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Fragile site in chromosome 12 in a patient with two miscarriages

Abstract

ASJC Scopus subject areas

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