FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate.

Lin Piao, Vaninder K. Sidhu, Yong Hu Fang, John J. Ryan, Kishan S. Parikh, Zhigang Hong, Peter T. Toth, Erik Morrow, Shelby Kutty, Gary D. Lopaschuk, Stephen L. Archer

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