Foveal Serous Retinal Detachment in Juvenile Idiopathic Arthritis-associated Uveitis

Feng Liang, Celine Terrada, Ghislaine Ducos de Lahitte, Pierre Quartier, Phuc Lehoang, Jennifer E. Thorne, Bahram Bodaghi

Research output: Contribution to journalArticle

Abstract

Purpose: In juvenile idiopathic arthritis (JIA)-associated uveitis complicated by foveal serous retinal detachment (FSRD), we documented the relationship between best corrected visual acuity (BCVA), level of anterior chamber flare and OCT features. Methods: Nine children (15 eyes) with FSRD were identified among 38 children with JIA-associated maculopathy. Outcome measures included BCVA, ocular inflammatory activity quantified by laser flare photometry and the macular profile analyzed by OCT. Results: The diagnosis of FSRD led to intensification of the treatment using subtenon’s injection of triamcinolone or systemic immunomodulatory therapy. The improvement of BCVA at presentation (0.46 logMAR) was significant at 36 months follow-up (0.15 logMAR). The resolution of FSRD along with visual improvement (p = 0.0032) correlated with improvement in anterior chamber flare (p = 0.01). Conclusion: FSRD is a complication of chronic JIA-associated uveitis that responds well to intensification of immunomodulation. Visual improvement is correlated with FSRD resolution and with flare photometry values.

Original languageEnglish (US)
Pages (from-to)386-391
Number of pages6
JournalOcular Immunology and Inflammation
Volume24
Issue number4
DOIs
StatePublished - Jul 3 2016

Keywords

  • Flare
  • OCT
  • foveal serous retinal detachment
  • juvenile idiopathic arthritis
  • uveitis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Ophthalmology

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