Fournier gangrene associated with Crohn disease

Tim Jiang, John A. Covington, Charles A. Haile, Joseph B. Murphy, Fhank S. Rotolo, Alan M. Lake

Research output: Contribution to journalArticle

Abstract

A 17-year-old boy presented with Fournier gangrene associated with previously undiagnosed Crohn ileocolitis. Fournier gangrene was managed by debridement, broad-spectrum antibiotics, and hyperbaric oxygen. A diverting ileostomy was performed before skin grafting and scrotal reconstruction. Microscopy of a full-layer surgical sample from the terminal ileum revealed granulomas with multinucleated histiocytes, consistent with Crohn disease. Crohn disease was treated with mesalamine, metronidazole, 6-mercaptopurine, and infliximab. The patient was discharged on hospital day 32. At 6-month follow-up, reconstruction of his scrotum had completely healed. Ostomy output was normal.

Original languageEnglish (US)
Pages (from-to)647-649
Number of pages3
JournalMayo Clinic Proceedings
Volume75
Issue number6
StatePublished - 2000

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Fournier Gangrene
Crohn Disease
Ostomy
Mesalamine
6-Mercaptopurine
Ileostomy
Skin Transplantation
Scrotum
Histiocytes
Metronidazole
Debridement
Granuloma
Ileum
Microscopy
Oxygen
Anti-Bacterial Agents

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Jiang, T., Covington, J. A., Haile, C. A., Murphy, J. B., Rotolo, F. S., & Lake, A. M. (2000). Fournier gangrene associated with Crohn disease. Mayo Clinic Proceedings, 75(6), 647-649.

Fournier gangrene associated with Crohn disease. / Jiang, Tim; Covington, John A.; Haile, Charles A.; Murphy, Joseph B.; Rotolo, Fhank S.; Lake, Alan M.

In: Mayo Clinic Proceedings, Vol. 75, No. 6, 2000, p. 647-649.

Research output: Contribution to journalArticle

Jiang, T, Covington, JA, Haile, CA, Murphy, JB, Rotolo, FS & Lake, AM 2000, 'Fournier gangrene associated with Crohn disease', Mayo Clinic Proceedings, vol. 75, no. 6, pp. 647-649.
Jiang T, Covington JA, Haile CA, Murphy JB, Rotolo FS, Lake AM. Fournier gangrene associated with Crohn disease. Mayo Clinic Proceedings. 2000;75(6):647-649.
Jiang, Tim ; Covington, John A. ; Haile, Charles A. ; Murphy, Joseph B. ; Rotolo, Fhank S. ; Lake, Alan M. / Fournier gangrene associated with Crohn disease. In: Mayo Clinic Proceedings. 2000 ; Vol. 75, No. 6. pp. 647-649.
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