Fournier gangrene associated with Crohn disease

Tim Jiang, John A. Covington, Charles A. Haile, Joseph B. Murphy, Fhank S. Rotolo, Alan M. Lake

Research output: Contribution to journalArticle


A 17-year-old boy presented with Fournier gangrene associated with previously undiagnosed Crohn ileocolitis. Fournier gangrene was managed by debridement, broad-spectrum antibiotics, and hyperbaric oxygen. A diverting ileostomy was performed before skin grafting and scrotal reconstruction. Microscopy of a full-layer surgical sample from the terminal ileum revealed granulomas with multinucleated histiocytes, consistent with Crohn disease. Crohn disease was treated with mesalamine, metronidazole, 6-mercaptopurine, and infliximab. The patient was discharged on hospital day 32. At 6-month follow-up, reconstruction of his scrotum had completely healed. Ostomy output was normal.

Original languageEnglish (US)
Pages (from-to)647-649
Number of pages3
JournalMayo Clinic proceedings
Issue number6
StatePublished - Jan 1 2000

ASJC Scopus subject areas

  • Medicine(all)

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    Jiang, T., Covington, J. A., Haile, C. A., Murphy, J. B., Rotolo, F. S., & Lake, A. M. (2000). Fournier gangrene associated with Crohn disease. Mayo Clinic proceedings, 75(6), 647-649.