Fourier domain versus time domain optical coherence tomography of the prostate nerves

Shahab Chitchian, Gwen Lagoda, Arthur Burnett, Nathaniel M. Fried

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations


Theoretical comparisons of detection performance for Fourier domain (FD) and time domain (TD) optical coherence tomography (OCT) have been previously reported. In this study, we compare several image quality metrics including signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and equivalent number of looks (ENL) for TD-OCT and FD-OCT images taken of the rat prostate, in vivo. The results show that TD-OCT has inferior CNR, but superior SNR compared to FD-OCT, and that TD-OCT is better for deep imaging of opaque tissues, including the prostate gland.

Original languageEnglish (US)
Title of host publicationPhotonic Therapeutics and Diagnostics VII
StatePublished - Apr 12 2011
EventPhotonic Therapeutics and Diagnostics VII - San Francisco, CA, United States
Duration: Jan 22 2011Jan 24 2011

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


OtherPhotonic Therapeutics and Diagnostics VII
Country/TerritoryUnited States
CitySan Francisco, CA


  • Fourier-domain
  • OCT
  • cavernous nerves
  • optical coherence tomography
  • prostate
  • time-domain

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging


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