Four novel HLA class II alleles identified using next-generation sequencing

Alison Gareau, Ahmad Abu-Khader, Guang Yang, Luz Stamm, Noureddine Berka

Research output: Contribution to journalArticlepeer-review

Abstract

We describe here four novel HLA class II alleles, DPA1*01:33, DPB1*1082:01, DPB1*1144:01, and DQA1*01:45, identified in our laboratory following the implementation of next generation sequencing (NGS) for routine high resolution HLA typing of donors and recipients for solid organ transplant and hematopoetic stem cell transplant. The NGS technology has improved our ability to match at all clinically HLA loci and to facilitate the interpretation of allele specific antibody and eplet matching.

Original languageEnglish (US)
Pages (from-to)233-234
Number of pages2
JournalHLA
Volume98
Issue number3
DOIs
StatePublished - Sep 2021
Externally publishedYes

Keywords

  • CLASS II
  • NGS
  • novel alleles

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Genetics

Fingerprint

Dive into the research topics of 'Four novel HLA class II alleles identified using next-generation sequencing'. Together they form a unique fingerprint.

Cite this