Four-dimensional respiratory motion-resolved whole heart coronary MR angiography

Davide Piccini, Li Feng, Gabriele Bonanno, Simone Coppo, Jérôme Yerly, Ruth P. Lim, Juerg Schwitter, Daniel K. Sodickson, Ricardo Otazo, Matthias Stuber

Research output: Contribution to journalArticle

Abstract

Purpose: Free-breathing whole-heart coronary MR angiography (MRA) commonly uses navigators to gate respiratory motion, resulting in lengthy and unpredictable acquisition times. Conversely, self-navigation has 100% scan efficiency, but requires motion correction over a broad range of respiratory displacements, which may introduce image artifacts. We propose replacing navigators and self-navigation with a respiratory motion-resolved reconstruction approach. Methods: Using a respiratory signal extracted directly from the imaging data, individual signal-readouts are binned according to their respiratory states. The resultant series of undersampled images are reconstructed using an extradimensional golden-angle radial sparse parallel imaging (XD-GRASP) algorithm, which exploits sparsity along the respiratory dimension. Whole-heart coronary MRA was performed in 11 volunteers and four patients with the proposed methodology. Image quality was compared with that obtained with one-dimensional respiratory self-navigation. Results: Respiratory-resolved reconstruction effectively suppressed respiratory motion artifacts. The quality score for XD-GRASP reconstructions was greater than or equal to self-navigation in 80/88 coronary segments, reaching diagnostic quality in 61/88 segments versus 41/88. Coronary sharpness and length were always superior for the respiratory-resolved datasets, reaching statistical significance (P <0.05) in most cases. Conclusion: XD-GRASP represents an attractive alternative for handling respiratory motion in free-breathing whole heart MRI and provides an effective alternative to self-navigation.

Original languageEnglish (US)
JournalMagnetic Resonance in Medicine
DOIs
StateAccepted/In press - 2016
Externally publishedYes

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Coronary Angiography
Artifacts
Respiration
Volunteers

Keywords

  • Compressed sensing
  • Coronary MRA
  • Free breathing
  • Motion correction
  • Self-navigation
  • Sparse reconstruction

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Piccini, D., Feng, L., Bonanno, G., Coppo, S., Yerly, J., Lim, R. P., ... Stuber, M. (Accepted/In press). Four-dimensional respiratory motion-resolved whole heart coronary MR angiography. Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.26221

Four-dimensional respiratory motion-resolved whole heart coronary MR angiography. / Piccini, Davide; Feng, Li; Bonanno, Gabriele; Coppo, Simone; Yerly, Jérôme; Lim, Ruth P.; Schwitter, Juerg; Sodickson, Daniel K.; Otazo, Ricardo; Stuber, Matthias.

In: Magnetic Resonance in Medicine, 2016.

Research output: Contribution to journalArticle

Piccini, D, Feng, L, Bonanno, G, Coppo, S, Yerly, J, Lim, RP, Schwitter, J, Sodickson, DK, Otazo, R & Stuber, M 2016, 'Four-dimensional respiratory motion-resolved whole heart coronary MR angiography', Magnetic Resonance in Medicine. https://doi.org/10.1002/mrm.26221
Piccini, Davide ; Feng, Li ; Bonanno, Gabriele ; Coppo, Simone ; Yerly, Jérôme ; Lim, Ruth P. ; Schwitter, Juerg ; Sodickson, Daniel K. ; Otazo, Ricardo ; Stuber, Matthias. / Four-dimensional respiratory motion-resolved whole heart coronary MR angiography. In: Magnetic Resonance in Medicine. 2016.
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