Foreign body granulomas secondary to retained sponge fragment following mitomycin C trabeculectomy

Sami Al-Shahwan, Deepak P. Edward

Research output: Contribution to journalArticle

Abstract

Background: Bleb related inflammation following trabeculectomy is usually seen in the late post operative period and is unusual in the first 6 months after surgery We report the clinical findings and course of two patients with early bleb related inflammation secondary to retained cellulose sponge fragments used to apply mitomycin C on the scleral surface. Methods: Retrospective review of medical records of two patients and pathology from one patient. Results: Both patients developed bleb related inflammation four months after a combined fornix based trabeculectomy and cataract procedure in which mitomycin C was applied using filter paper discs (Whatman filter paper #1). Material suggestive of cellulose fragments was noted in the filtering bleb in both patients. Patient 1 had a bleb leak at time of presentation and pathologic examination of foreign body material obtained from the site of the leak demonstrated a granulomatous reaction surrounding cellulose fibers. The foreign body material was removed in both patients. This led to resolution of the bleb leak in the first patient and at one year following the procedure both patients had functioning blebs in the affected eye. Conclusions: Retention of sponge fragments is rare but may be a cause of bleb inflammation as a result of a foreign body granulomatous reaction. The choice of sponge material that does not shred may help in avoiding this unusual complication.

Original languageEnglish (US)
Pages (from-to)178-181
Number of pages4
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Volume243
Issue number2
DOIs
StatePublished - Feb 2005
Externally publishedYes

Fingerprint

Foreign-Body Granuloma
Trabeculectomy
Porifera
Mitomycin
Blister
Cellulose
Inflammation
Foreign Bodies
Foreign-Body Reaction
Cataract
Medical Records
Pathology

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Foreign body granulomas secondary to retained sponge fragment following mitomycin C trabeculectomy. / Al-Shahwan, Sami; Edward, Deepak P.

In: Graefe's Archive for Clinical and Experimental Ophthalmology, Vol. 243, No. 2, 02.2005, p. 178-181.

Research output: Contribution to journalArticle

@article{c7388a554a904234bb46da6f9df2983f,
title = "Foreign body granulomas secondary to retained sponge fragment following mitomycin C trabeculectomy",
abstract = "Background: Bleb related inflammation following trabeculectomy is usually seen in the late post operative period and is unusual in the first 6 months after surgery We report the clinical findings and course of two patients with early bleb related inflammation secondary to retained cellulose sponge fragments used to apply mitomycin C on the scleral surface. Methods: Retrospective review of medical records of two patients and pathology from one patient. Results: Both patients developed bleb related inflammation four months after a combined fornix based trabeculectomy and cataract procedure in which mitomycin C was applied using filter paper discs (Whatman filter paper #1). Material suggestive of cellulose fragments was noted in the filtering bleb in both patients. Patient 1 had a bleb leak at time of presentation and pathologic examination of foreign body material obtained from the site of the leak demonstrated a granulomatous reaction surrounding cellulose fibers. The foreign body material was removed in both patients. This led to resolution of the bleb leak in the first patient and at one year following the procedure both patients had functioning blebs in the affected eye. Conclusions: Retention of sponge fragments is rare but may be a cause of bleb inflammation as a result of a foreign body granulomatous reaction. The choice of sponge material that does not shred may help in avoiding this unusual complication.",
author = "Sami Al-Shahwan and Edward, {Deepak P.}",
year = "2005",
month = "2",
doi = "10.1007/s00417-004-1011-y",
language = "English (US)",
volume = "243",
pages = "178--181",
journal = "Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie",
issn = "0721-832X",
publisher = "Springer Verlag",
number = "2",

}

TY - JOUR

T1 - Foreign body granulomas secondary to retained sponge fragment following mitomycin C trabeculectomy

AU - Al-Shahwan, Sami

AU - Edward, Deepak P.

PY - 2005/2

Y1 - 2005/2

N2 - Background: Bleb related inflammation following trabeculectomy is usually seen in the late post operative period and is unusual in the first 6 months after surgery We report the clinical findings and course of two patients with early bleb related inflammation secondary to retained cellulose sponge fragments used to apply mitomycin C on the scleral surface. Methods: Retrospective review of medical records of two patients and pathology from one patient. Results: Both patients developed bleb related inflammation four months after a combined fornix based trabeculectomy and cataract procedure in which mitomycin C was applied using filter paper discs (Whatman filter paper #1). Material suggestive of cellulose fragments was noted in the filtering bleb in both patients. Patient 1 had a bleb leak at time of presentation and pathologic examination of foreign body material obtained from the site of the leak demonstrated a granulomatous reaction surrounding cellulose fibers. The foreign body material was removed in both patients. This led to resolution of the bleb leak in the first patient and at one year following the procedure both patients had functioning blebs in the affected eye. Conclusions: Retention of sponge fragments is rare but may be a cause of bleb inflammation as a result of a foreign body granulomatous reaction. The choice of sponge material that does not shred may help in avoiding this unusual complication.

AB - Background: Bleb related inflammation following trabeculectomy is usually seen in the late post operative period and is unusual in the first 6 months after surgery We report the clinical findings and course of two patients with early bleb related inflammation secondary to retained cellulose sponge fragments used to apply mitomycin C on the scleral surface. Methods: Retrospective review of medical records of two patients and pathology from one patient. Results: Both patients developed bleb related inflammation four months after a combined fornix based trabeculectomy and cataract procedure in which mitomycin C was applied using filter paper discs (Whatman filter paper #1). Material suggestive of cellulose fragments was noted in the filtering bleb in both patients. Patient 1 had a bleb leak at time of presentation and pathologic examination of foreign body material obtained from the site of the leak demonstrated a granulomatous reaction surrounding cellulose fibers. The foreign body material was removed in both patients. This led to resolution of the bleb leak in the first patient and at one year following the procedure both patients had functioning blebs in the affected eye. Conclusions: Retention of sponge fragments is rare but may be a cause of bleb inflammation as a result of a foreign body granulomatous reaction. The choice of sponge material that does not shred may help in avoiding this unusual complication.

UR - http://www.scopus.com/inward/record.url?scp=14944363304&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=14944363304&partnerID=8YFLogxK

U2 - 10.1007/s00417-004-1011-y

DO - 10.1007/s00417-004-1011-y

M3 - Article

C2 - 15378381

AN - SCOPUS:14944363304

VL - 243

SP - 178

EP - 181

JO - Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie

JF - Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie

SN - 0721-832X

IS - 2

ER -