Force-sensing microneedle for assisted retinal vein cannulation

Berk Gonenc, Russell H. Taylor, Iulian Iordachita, Peter Gehlbach, James Handa

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Retinal vein cannulation (RVC) is a challenging procedure proposed for drug delivery into the very small retinal veins. The available glass cannulas for this procedure are both hard to visualize and fragile thereby limiting the feasibility of both robot-assisted and manual RVC approaches. In this study, we develop and test a new force-sensing RVC instrument that can be easily integrated with the existing manual and robotic devices. The tool enables (1) the measurement of the forces required for puncturing retinal veins in vivo and (2) an assistive method to inform the operator of the needle piercing the vessel wall. The fiber Bragg grating based sensor can be inserted into the eye through a small (Ø 0.9 mm) opening and provides a quantitative assessment at the tool tip with a resolution smaller than 0.25 mN. Assessment of forces during vessel penetration in the chorioallantoic membranes of chicken embryos have revealed a consistent sharp drop in tool tip force upon vessel puncture that has been used as a signature to provide auditory feedback to the user to stop needle advancement and begin drug delivery.

Original languageEnglish (US)
Title of host publicationIEEE SENSORS 2014, Proceedings
EditorsFrancisco J. Arregui
PublisherInstitute of Electrical and Electronics Engineers Inc.
Number of pages4
ISBN (Electronic)9781479901616
StatePublished - Dec 12 2014
Event13th IEEE SENSORS Conference, SENSORS 2014 - Valencia, Spain
Duration: Nov 2 2014Nov 5 2014

Publication series

NameProceedings of IEEE Sensors
ISSN (Print)1930-0395
ISSN (Electronic)2168-9229


Other13th IEEE SENSORS Conference, SENSORS 2014


  • Fiber Bragg grating
  • Force sensing
  • Vein cannulation

ASJC Scopus subject areas

  • Electrical and Electronic Engineering


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