Force-sensing microneedle for assisted retinal vein cannulation

Berk Gonenc, Russell H Taylor, Iulian Iordachita, Peter Gehlbach, James Handa

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Retinal vein cannulation (RVC) is a challenging procedure proposed for drug delivery into the very small retinal veins. The available glass cannulas for this procedure are both hard to visualize and fragile thereby limiting the feasibility of both robot-assisted and manual RVC approaches. In this study, we develop and test a new force-sensing RVC instrument that can be easily integrated with the existing manual and robotic devices. The tool enables (1) the measurement of the forces required for puncturing retinal veins in vivo and (2) an assistive method to inform the operator of the needle piercing the vessel wall. The fiber Bragg grating based sensor can be inserted into the eye through a small (Ø 0.9 mm) opening and provides a quantitative assessment at the tool tip with a resolution smaller than 0.25 mN. Assessment of forces during vessel penetration in the chorioallantoic membranes of chicken embryos have revealed a consistent sharp drop in tool tip force upon vessel puncture that has been used as a signature to provide auditory feedback to the user to stop needle advancement and begin drug delivery.

Original languageEnglish (US)
Title of host publicationProceedings of IEEE Sensors
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages698-701
Number of pages4
Volume2014-December
EditionDecember
DOIs
StatePublished - Dec 12 2014
Event13th IEEE SENSORS Conference, SENSORS 2014 - Valencia, Spain
Duration: Nov 2 2014Nov 5 2014

Other

Other13th IEEE SENSORS Conference, SENSORS 2014
CountrySpain
CityValencia
Period11/2/1411/5/14

Fingerprint

Piercing
Drug delivery
Needles
Fiber Bragg gratings
Robotics
Robots
Membranes
Feedback
Glass
Sensors

Keywords

  • Fiber Bragg grating
  • Force sensing
  • Vein cannulation

ASJC Scopus subject areas

  • Electrical and Electronic Engineering

Cite this

Gonenc, B., Taylor, R. H., Iordachita, I., Gehlbach, P., & Handa, J. (2014). Force-sensing microneedle for assisted retinal vein cannulation. In Proceedings of IEEE Sensors (December ed., Vol. 2014-December, pp. 698-701). [6985095] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/ICSENS.2014.6985095

Force-sensing microneedle for assisted retinal vein cannulation. / Gonenc, Berk; Taylor, Russell H; Iordachita, Iulian; Gehlbach, Peter; Handa, James.

Proceedings of IEEE Sensors. Vol. 2014-December December. ed. Institute of Electrical and Electronics Engineers Inc., 2014. p. 698-701 6985095.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Gonenc, B, Taylor, RH, Iordachita, I, Gehlbach, P & Handa, J 2014, Force-sensing microneedle for assisted retinal vein cannulation. in Proceedings of IEEE Sensors. December edn, vol. 2014-December, 6985095, Institute of Electrical and Electronics Engineers Inc., pp. 698-701, 13th IEEE SENSORS Conference, SENSORS 2014, Valencia, Spain, 11/2/14. https://doi.org/10.1109/ICSENS.2014.6985095
Gonenc B, Taylor RH, Iordachita I, Gehlbach P, Handa J. Force-sensing microneedle for assisted retinal vein cannulation. In Proceedings of IEEE Sensors. December ed. Vol. 2014-December. Institute of Electrical and Electronics Engineers Inc. 2014. p. 698-701. 6985095 https://doi.org/10.1109/ICSENS.2014.6985095
Gonenc, Berk ; Taylor, Russell H ; Iordachita, Iulian ; Gehlbach, Peter ; Handa, James. / Force-sensing microneedle for assisted retinal vein cannulation. Proceedings of IEEE Sensors. Vol. 2014-December December. ed. Institute of Electrical and Electronics Engineers Inc., 2014. pp. 698-701
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