@inproceedings{03029280e8ad4817ae6abde758d136f5,
title = "Force-sensing microneedle for assisted retinal vein cannulation",
abstract = "Retinal vein cannulation (RVC) is a challenging procedure proposed for drug delivery into the very small retinal veins. The available glass cannulas for this procedure are both hard to visualize and fragile thereby limiting the feasibility of both robot-assisted and manual RVC approaches. In this study, we develop and test a new force-sensing RVC instrument that can be easily integrated with the existing manual and robotic devices. The tool enables (1) the measurement of the forces required for puncturing retinal veins in vivo and (2) an assistive method to inform the operator of the needle piercing the vessel wall. The fiber Bragg grating based sensor can be inserted into the eye through a small ({\O} 0.9 mm) opening and provides a quantitative assessment at the tool tip with a resolution smaller than 0.25 mN. Assessment of forces during vessel penetration in the chorioallantoic membranes of chicken embryos have revealed a consistent sharp drop in tool tip force upon vessel puncture that has been used as a signature to provide auditory feedback to the user to stop needle advancement and begin drug delivery.",
keywords = "Fiber Bragg grating, Force sensing, Vein cannulation",
author = "Berk Gonenc and Taylor, {Russell H.} and Iulian Iordachita and Peter Gehlbach and James Handa",
note = "Publisher Copyright: {\textcopyright} 2014 IEEE.; 13th IEEE SENSORS Conference, SENSORS 2014 ; Conference date: 02-11-2014 Through 05-11-2014",
year = "2014",
month = dec,
day = "12",
doi = "10.1109/ICSENS.2014.6985095",
language = "English (US)",
series = "Proceedings of IEEE Sensors",
publisher = "Institute of Electrical and Electronics Engineers Inc.",
number = "December",
pages = "698--701",
editor = "Arregui, {Francisco J.}",
booktitle = "IEEE SENSORS 2014, Proceedings",
edition = "December",
}