Focal glomerulosclerosis and erythrocytosis

D. I. Myers, A. A. Ciuffo, C. R. Cooke

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

A 22-year-old black male presented with erythrocytosis and proteinuria. The erythrocytosis was characterized by increased red cell mass, normal arterial oxygen saturation, and normal hemoglobin electrophoresis and oxygen affinity. There was no splenomegaly, and the white blood cell count, platelet count, serum uric acid concentration, serum B12 levels and leukocyte alkaline phosphatase activity were normal. Tumors of the liver, lung, kidney and cerebellum, which have been associated with erythrocytosis, were not found. The only associated disease was biopsy proven focal glomerulosclerosis. Renal vein thrombosis was excluded by renal venography and arteriography. This case illustrates the rarely reported association of the nephrotic syndrome and erythrocytosis. Other nephrogenic causes of erythrocytosis are mentioned, including renal cysts, tumors, renal artery stenosis and transplantation. The role of the kidney in erythropoietin production and possible mechanisms of nephrogenic erythrocytosis are discussed.

Original languageEnglish (US)
Title of host publicationJohns Hopkins Medical Journal
Pages192-195
Number of pages4
Volume145
Edition5
StatePublished - 1979

Fingerprint

Focal Segmental Glomerulosclerosis
Polycythemia
Kidney
Erythrocyte Volume
Oxygen
Renal Artery Obstruction
Renal Veins
Phlebography
Splenomegaly
Nephrotic Syndrome
Erythropoietin
Uric Acid
Serum
Platelet Count
Leukocyte Count
Proteinuria
Kidney Transplantation
Cerebellum
Alkaline Phosphatase
Electrophoresis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Myers, D. I., Ciuffo, A. A., & Cooke, C. R. (1979). Focal glomerulosclerosis and erythrocytosis. In Johns Hopkins Medical Journal (5 ed., Vol. 145, pp. 192-195)

Focal glomerulosclerosis and erythrocytosis. / Myers, D. I.; Ciuffo, A. A.; Cooke, C. R.

Johns Hopkins Medical Journal. Vol. 145 5. ed. 1979. p. 192-195.

Research output: Chapter in Book/Report/Conference proceedingChapter

Myers, DI, Ciuffo, AA & Cooke, CR 1979, Focal glomerulosclerosis and erythrocytosis. in Johns Hopkins Medical Journal. 5 edn, vol. 145, pp. 192-195.
Myers DI, Ciuffo AA, Cooke CR. Focal glomerulosclerosis and erythrocytosis. In Johns Hopkins Medical Journal. 5 ed. Vol. 145. 1979. p. 192-195
Myers, D. I. ; Ciuffo, A. A. ; Cooke, C. R. / Focal glomerulosclerosis and erythrocytosis. Johns Hopkins Medical Journal. Vol. 145 5. ed. 1979. pp. 192-195
@inbook{c0c3476d5395470b9e4a53b9b81621aa,
title = "Focal glomerulosclerosis and erythrocytosis",
abstract = "A 22-year-old black male presented with erythrocytosis and proteinuria. The erythrocytosis was characterized by increased red cell mass, normal arterial oxygen saturation, and normal hemoglobin electrophoresis and oxygen affinity. There was no splenomegaly, and the white blood cell count, platelet count, serum uric acid concentration, serum B12 levels and leukocyte alkaline phosphatase activity were normal. Tumors of the liver, lung, kidney and cerebellum, which have been associated with erythrocytosis, were not found. The only associated disease was biopsy proven focal glomerulosclerosis. Renal vein thrombosis was excluded by renal venography and arteriography. This case illustrates the rarely reported association of the nephrotic syndrome and erythrocytosis. Other nephrogenic causes of erythrocytosis are mentioned, including renal cysts, tumors, renal artery stenosis and transplantation. The role of the kidney in erythropoietin production and possible mechanisms of nephrogenic erythrocytosis are discussed.",
author = "Myers, {D. I.} and Ciuffo, {A. A.} and Cooke, {C. R.}",
year = "1979",
language = "English (US)",
volume = "145",
pages = "192--195",
booktitle = "Johns Hopkins Medical Journal",
edition = "5",

}

TY - CHAP

T1 - Focal glomerulosclerosis and erythrocytosis

AU - Myers, D. I.

AU - Ciuffo, A. A.

AU - Cooke, C. R.

PY - 1979

Y1 - 1979

N2 - A 22-year-old black male presented with erythrocytosis and proteinuria. The erythrocytosis was characterized by increased red cell mass, normal arterial oxygen saturation, and normal hemoglobin electrophoresis and oxygen affinity. There was no splenomegaly, and the white blood cell count, platelet count, serum uric acid concentration, serum B12 levels and leukocyte alkaline phosphatase activity were normal. Tumors of the liver, lung, kidney and cerebellum, which have been associated with erythrocytosis, were not found. The only associated disease was biopsy proven focal glomerulosclerosis. Renal vein thrombosis was excluded by renal venography and arteriography. This case illustrates the rarely reported association of the nephrotic syndrome and erythrocytosis. Other nephrogenic causes of erythrocytosis are mentioned, including renal cysts, tumors, renal artery stenosis and transplantation. The role of the kidney in erythropoietin production and possible mechanisms of nephrogenic erythrocytosis are discussed.

AB - A 22-year-old black male presented with erythrocytosis and proteinuria. The erythrocytosis was characterized by increased red cell mass, normal arterial oxygen saturation, and normal hemoglobin electrophoresis and oxygen affinity. There was no splenomegaly, and the white blood cell count, platelet count, serum uric acid concentration, serum B12 levels and leukocyte alkaline phosphatase activity were normal. Tumors of the liver, lung, kidney and cerebellum, which have been associated with erythrocytosis, were not found. The only associated disease was biopsy proven focal glomerulosclerosis. Renal vein thrombosis was excluded by renal venography and arteriography. This case illustrates the rarely reported association of the nephrotic syndrome and erythrocytosis. Other nephrogenic causes of erythrocytosis are mentioned, including renal cysts, tumors, renal artery stenosis and transplantation. The role of the kidney in erythropoietin production and possible mechanisms of nephrogenic erythrocytosis are discussed.

UR - http://www.scopus.com/inward/record.url?scp=0018642325&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018642325&partnerID=8YFLogxK

M3 - Chapter

C2 - 502118

AN - SCOPUS:0018642325

VL - 145

SP - 192

EP - 195

BT - Johns Hopkins Medical Journal

ER -