fMRI characterization of the language formulation area

Joseph Dien; Michael S. Franklin; Charles A. Michelson; Lisa C. Lemen; Christy L. Adams; Kent A. Kiehl

doi:10.1016/j.brainres.2008.06.107

fMRI characterization of the language formulation area

Joseph Dien, Michael S. Franklin, Charles A. Michelson, Lisa C. Lemen, Christy L. Adams, Kent A. Kiehl

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Participants read sentences presented one word at a time, half of which ended with a semantically incongruent ending. 1.5T functional magnetic resonance imaging data were collected from 11 participants, showing that the left posterior inferior temporal region, which has previously been termed the Language Formulation Area (LFA), responded to cloze probability. It is suggested, based on anatomical positioning and a literature review, that the responsiveness of the LFA to cloze probabilities may reflect a role in coordinating the lexical and non-lexical reading pathways. Finally, it is noted that previous studies have implicated this region in dyslexia and some speculations are made in this regard.

Original language	English (US)
Pages (from-to)	179-192
Number of pages	14
Journal	Brain research
Volume	1229
DOIs	https://doi.org/10.1016/j.brainres.2008.06.107
State	Published - Sep 10 2008

Keywords

Dyslexia
Language
Sentence
fMRI

ASJC Scopus subject areas

Neuroscience(all)
Molecular Biology
Clinical Neurology
Developmental Biology

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title = "fMRI characterization of the language formulation area",

abstract = "Participants read sentences presented one word at a time, half of which ended with a semantically incongruent ending. 1.5T functional magnetic resonance imaging data were collected from 11 participants, showing that the left posterior inferior temporal region, which has previously been termed the Language Formulation Area (LFA), responded to cloze probability. It is suggested, based on anatomical positioning and a literature review, that the responsiveness of the LFA to cloze probabilities may reflect a role in coordinating the lexical and non-lexical reading pathways. Finally, it is noted that previous studies have implicated this region in dyslexia and some speculations are made in this regard.",

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AU - Dien, Joseph

AU - Franklin, Michael S.

AU - Michelson, Charles A.

AU - Lemen, Lisa C.

AU - Adams, Christy L.

AU - Kiehl, Kent A.

PY - 2008/9/10

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AB - Participants read sentences presented one word at a time, half of which ended with a semantically incongruent ending. 1.5T functional magnetic resonance imaging data were collected from 11 participants, showing that the left posterior inferior temporal region, which has previously been termed the Language Formulation Area (LFA), responded to cloze probability. It is suggested, based on anatomical positioning and a literature review, that the responsiveness of the LFA to cloze probabilities may reflect a role in coordinating the lexical and non-lexical reading pathways. Finally, it is noted that previous studies have implicated this region in dyslexia and some speculations are made in this regard.

KW - Dyslexia

KW - Language

KW - Sentence

KW - fMRI

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fMRI characterization of the language formulation area

Abstract

Keywords

ASJC Scopus subject areas

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