Abstract
A diffused optical detection system for fluorescence imaging of lesions, deep beneath the tissue surface, was discussed. The conjugate interacts with the antigens expressed by the diseased tissue, resulting in fluorescent labeling of the antigen. The position of the fluorophore in the tissue was also determined by using the fluorescence imaging combined with a reconstruction algorithm developed on the bases of the random walk model. An application of a tool, based on the random-walk theory in turbid media, for extracting the pharmacokinetics of the fluorescent antibodies by data deconvolution, was also presented.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 898-899 |
| Number of pages | 2 |
| Journal | Conference Proceedings - Lasers and Electro-Optics Society Annual Meeting-LEOS |
| Volume | 2 |
| State | Published - Dec 1 2004 |
| Externally published | Yes |
| Event | 2004 IEEE LEOS Annual Meeting Conference Proceedings, LEOS 2004 - Rio Grande, Puerto Rico Duration: Nov 7 2004 → Nov 11 2004 |
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Electrical and Electronic Engineering