Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome

Colin K. Grissom, Eliotte L. Hirshberg, Justin B. Dickerson, Samuel M. Brown, Michael J. Lanspa, Kathleen D. Liu, David Schoenfeld, Mark Tidswell, R. Duncan Hite, Peter Rock, Russell R. Miller, Alan H. Morris, L. Hudson, S. Gundel, C. Hough, M. Neff, K. Sims, A. Ungar, T. Watkins, J. SteingrubM. Tidswell, E. Braden, L. DeSouza, J. Germain, C. Kardos, D. Kelley, L. Kozikowski, S. Ouellette, K. Guntupalli, V. Bandi, C. Pope, C. Ross, R. Brower, H. Fessler, D. Hager, P. Mendez-Tellez, D. Needham, K. Oakjones, J. Sevransky, A. Workneh, C. Shanholtz, D. Herr, H. Howes, G. Netzer, P. Rock, A. Sampaio, J. Titus, P. Sloane, T. Beck, H. Highfield, S. King, B. Lee, N. Bolouri, H. P. Wiedemann, R. W. Ashton, D. A. Culver, T. Frederick, J. A. Guzman, J. J. Komara, A. J. Reddy, R. Hejal, M. Andrews, D. Haney, A. F. Connors, S. Lasalvia, J. D. Thornton, E. L. Warren, M. Moss, E. L. Burnham, L. Gray, J. Maloney, M. Mealer, I. Douglas, K. Overdier, K. Thompson, R. Wolken, S. Frankel, J. McKeehan, M. L. Warner, T. Bost, C. Higgins, K. Hodgin, N. MacIntyre, L. Brown, C. Cox, M. Gentile, J. Govert, N. Knudsen, S. Carson, L. Chang, S. Choudhury, W. Hall, J. Lanier, A. P. Wheeler, G. R. Bernard, M. Hays, S. Mogan, T. Rice, R. D. Hite, K. Bender, A. Harvey, P. E. Morris, Mary Ragusky, P. Wright, S. Groce, J. McLean, A. Overton, J. Truwit, K. Enfield, M. Marshall, A. Morris, A. Austin, S. Barney, S. Brown, J. Ferguson, H. Gallo, T. Graydon, C. Grissom, E. Hirshberg, A. Jephson, N. Kumar, R. Miller, D. Murphy, J. Orme, A. Stowe, L. Struck, F. Thomas, D. Ward, L. Weaver, P. Bailey, W. Beninati, L. Bezdijan, T. Clemmer, S. Rimkus, R. Tanaka, C. Lawton, D. Hanselman, K. Sundar, W. Alward, C. Bishop, D. Eckley, T. Hill, B. Jensen, K. Ludwig, D. Nielsen, M. Pearce, M. A. Matthay, C. Calfee, B. Daniel, M. Eisner, O. Garcia, K. Kordesch, K. Liu, N. Shum, H. Zhou, M. W. Peterson, J. Blaauw, K. Van Gundy, T. Albertson, B. Morrissey, E. Vlastelin, R. Hubmayr, D. Brown, M. Dubin, E. Festic, O. Gajic, R. Hinds, S. Holets, D. Kor, A. Lee, M. Passe, G. Simpson, J. Wright, B. DeBoisblanc, A. Antoine, D. Charbonnet, J. Hunt, P. Lauto, A. Marr, G. Meyaski, C. Romaine, R. Tejedor, S. Brierre, J. Byrne, T. Jagneaux, C. LeBlanc, K. Moreau, C. Thomas, S. Jain, D. Taylor, L. Seoane, C. Hebert, J. Thompson, F. Simeone, J. Fearon, D. Schoenfeld, M. Guha, E. Hammond, N. Lavery, P. Lazar, R. Morse, C. Oldmixon, N. Ringwood, E. Smoot, B. T. Thompson, R. Wilson, A. Harabin, S. Bredow, M. Waclawiw, G. Weinmann

Research output: Contribution to journalArticle

Abstract

Objectives: In the Fluid and Catheter Treatment Trial (FACTT) of the National Institutes of Health Acute Respiratory Distress Syndrome Network, a conservative fluid protocol (FACTT Conservative) resulted in a lower cumulative fluid balance and better outcomes than a liberal fluid protocol (FACTT Liberal). Subsequent Acute Respiratory Distress Syndrome Network studies used a simplified conservative fluid protocol (FACTT Lite). The objective of this study was to compare the performance of FACTT Lite, FACTT Conservative, and FACTT Liberal protocols.

Original languageEnglish (US)
Pages (from-to)288-295
Number of pages8
JournalCritical care medicine
Volume43
Issue number2
DOIs
StatePublished - Feb 1 2015

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Keywords

  • Acute kidney injury
  • Adult respiratory distress syndrome
  • Clinical protocols
  • Critical illness
  • Fluid therapy
  • Shock

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine

Cite this

Grissom, C. K., Hirshberg, E. L., Dickerson, J. B., Brown, S. M., Lanspa, M. J., Liu, K. D., Schoenfeld, D., Tidswell, M., Hite, R. D., Rock, P., Miller, R. R., Morris, A. H., Hudson, L., Gundel, S., Hough, C., Neff, M., Sims, K., Ungar, A., Watkins, T., ... Weinmann, G. (2015). Fluid management with a simplified conservative protocol for the acute respiratory distress syndrome. Critical care medicine, 43(2), 288-295. https://doi.org/10.1097/CCM.0000000000000715