TY - JOUR
T1 - Flexible tantalum stents implanted in aortas and iliac arteries
T2 - Effects in normal canines
AU - Barth, Klemens H.
AU - Virmani, Renu
AU - Strecker, Ernst P.
AU - Savin, Michael A.
AU - Lindisch, David
AU - Matsumoto, Alan H.
AU - Teitelbaum, George P.
PY - 1990/4
Y1 - 1990/4
N2 - Vascular endoprostheses made of knitted tantalum wire and expanded over angioplasty balloons were placed into aortas or iliac arteries of 14 normal dogs. Twelve stents were placed into the infrarenal abdominal aorta and two stents in the left common iliac arteries by the left carotid artery approach. To firmly expand the stent against the vascular wall, nominal stent sizes 0.5-1.0 mm larger than the measured arterial diameter were required. Arteriography performed at specified followup intervals showed no evidence of thrombi or emboli; all side branches (lumbar arteries) covered by the stents remained patent. Vascular diameter decreased minimally at 8 and 26 weeks, associated with histopathologic evidence of neointimal buildup. This buildup was highest at 8 weeks (mean, 313 μM) and was slightly less at 26 weeks (mean, 223 μm). Almost complete coverage by endothelium was seen as early as 3 weeks. It is concluded that the flexible tantalum wire stents are well tolerated by the arterial wall and become quickly endothelialized. No excessive neointimal buildup was observed during the 6-month study.
AB - Vascular endoprostheses made of knitted tantalum wire and expanded over angioplasty balloons were placed into aortas or iliac arteries of 14 normal dogs. Twelve stents were placed into the infrarenal abdominal aorta and two stents in the left common iliac arteries by the left carotid artery approach. To firmly expand the stent against the vascular wall, nominal stent sizes 0.5-1.0 mm larger than the measured arterial diameter were required. Arteriography performed at specified followup intervals showed no evidence of thrombi or emboli; all side branches (lumbar arteries) covered by the stents remained patent. Vascular diameter decreased minimally at 8 and 26 weeks, associated with histopathologic evidence of neointimal buildup. This buildup was highest at 8 weeks (mean, 313 μM) and was slightly less at 26 weeks (mean, 223 μm). Almost complete coverage by endothelium was seen as early as 3 weeks. It is concluded that the flexible tantalum wire stents are well tolerated by the arterial wall and become quickly endothelialized. No excessive neointimal buildup was observed during the 6-month study.
KW - Aorta, grafts and prostheses, 89.459, 98.456
KW - Arteries, grafts and prostheses
KW - Arteries, iliac, 98.456
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U2 - 10.1148/radiology.175.1.2315508
DO - 10.1148/radiology.175.1.2315508
M3 - Article
C2 - 2315508
AN - SCOPUS:0025341891
SN - 0033-8419
VL - 175
SP - 91
EP - 96
JO - RADIOLOGY
JF - RADIOLOGY
IS - 1
ER -