Five year follow-up after valve replacement with the St. Jude Medical valve in infants and children

A. M. Borkon, L. Soule, B. A. Reitz, Vincent L Gott, T. J. Gardner

Research output: Contribution to journalArticle

Abstract

Since 1979, 34 infants and children, 3 weeks to 17 years of age, have undergone cardiac valve raplacement with a St. Jude Medical (SJM) prosthesis at our institution. Seventeen children underwent mitral valve replacement (MVR), 16 aorta valve replacement (AVR), and one pulmonary valve replacement. Three hospital deaths were associated with MVR and complex congenital heart disease. All surviving patients were functional in class I. A cumulative 89.1 patient-years of follow-up were analyzed to evaluated valve-related mortality and morbidity. Late complications included thromboembolus (one patient), anticoagulant-related hemorrhage (one patient), and perivalvular leak (one patient). One of six late deaths resulted from mitral valve thrombosis. Actuarial 5 year survival for patients who underwent AVR was 100%, but it was 53% for MVR (p = .03). Freedom from significant morbidity and mortality for up to 5 years after operation was 92 ± 7% for those who underwent AVR and 45 ± 16% for those who underwent MVR. Patient-related factors appear to account for an increased rate of complications after MVR. Because of difficulties with achieving anticoagulation with warfarin, aspirin therapy should be used for patients less than 5 years of age, while older patients can be managed with warfarin. The SJM valve is a satisfactory cardiac valve substitute for the pediatric age group.

Original languageEnglish (US)
Pages (from-to)110-115
Number of pages6
JournalCirculation
Volume74
Issue number3 II MONOGR. 123
Publication statusPublished - 1986
Externally publishedYes

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ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Borkon, A. M., Soule, L., Reitz, B. A., Gott, V. L., & Gardner, T. J. (1986). Five year follow-up after valve replacement with the St. Jude Medical valve in infants and children. Circulation, 74(3 II MONOGR. 123), 110-115.