Abstract
We report the prenatal diagnosis of twin-to-twin transfusion syndrome (TTS) at 11 weeks' gestation. The diagnosis was made in a trichorionic quadruplet pregnancy which was conceived after in vitro fertilization and intra-cytoplasmic sperm injection for male subfertility and transfer of 3 embryos. Growth discordance, oligo/polyhydramnios and abnormal arterial and venous Doppler flows were demonstrated in 2 monochorionic fetuses, while the remaining 2 dichorionic fetuses were unremarkable. Selective fetocide of the donor by intracardiac injection of potassium chloride was followed by the spontaneous demise of the recipient. The pregnancy course remained uneventful until 32 weeks of gestation when the patient developed preterm labor. Two healthy preterm babies were delivered by cesarean section. The diagnostic problems of this early manifestation of TTS are discussed.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 357-361 |
| Number of pages | 5 |
| Journal | Fetal Diagnosis and Therapy |
| Volume | 17 |
| Issue number | 6 |
| DOIs | |
| State | Published - 2002 |
| Externally published | Yes |
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Keywords
- Assisted reproduction
- First trimester
- Quadruplet pregnancy
- Twin-to-twin transfusion syndrome
- Ultrasound
ASJC Scopus subject areas
- Obstetrics and Gynecology
- Pediatrics, Perinatology, and Child Health
Cite this
First trimester twin-to-twin transfusion syndrome in a trichorionic quadruplet pregnancy - A diagnostic challenge. / Berg, Cristoph; Baschat, Ahmet; Geipel, A.; Germer, U.; Smrcek, J.; Krapp, M.; Gembruch, U.
In: Fetal Diagnosis and Therapy, Vol. 17, No. 6, 2002, p. 357-361.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - First trimester twin-to-twin transfusion syndrome in a trichorionic quadruplet pregnancy - A diagnostic challenge
AU - Berg, Cristoph
AU - Baschat, Ahmet
AU - Geipel, A.
AU - Germer, U.
AU - Smrcek, J.
AU - Krapp, M.
AU - Gembruch, U.
PY - 2002
Y1 - 2002
N2 - We report the prenatal diagnosis of twin-to-twin transfusion syndrome (TTS) at 11 weeks' gestation. The diagnosis was made in a trichorionic quadruplet pregnancy which was conceived after in vitro fertilization and intra-cytoplasmic sperm injection for male subfertility and transfer of 3 embryos. Growth discordance, oligo/polyhydramnios and abnormal arterial and venous Doppler flows were demonstrated in 2 monochorionic fetuses, while the remaining 2 dichorionic fetuses were unremarkable. Selective fetocide of the donor by intracardiac injection of potassium chloride was followed by the spontaneous demise of the recipient. The pregnancy course remained uneventful until 32 weeks of gestation when the patient developed preterm labor. Two healthy preterm babies were delivered by cesarean section. The diagnostic problems of this early manifestation of TTS are discussed.
AB - We report the prenatal diagnosis of twin-to-twin transfusion syndrome (TTS) at 11 weeks' gestation. The diagnosis was made in a trichorionic quadruplet pregnancy which was conceived after in vitro fertilization and intra-cytoplasmic sperm injection for male subfertility and transfer of 3 embryos. Growth discordance, oligo/polyhydramnios and abnormal arterial and venous Doppler flows were demonstrated in 2 monochorionic fetuses, while the remaining 2 dichorionic fetuses were unremarkable. Selective fetocide of the donor by intracardiac injection of potassium chloride was followed by the spontaneous demise of the recipient. The pregnancy course remained uneventful until 32 weeks of gestation when the patient developed preterm labor. Two healthy preterm babies were delivered by cesarean section. The diagnostic problems of this early manifestation of TTS are discussed.
KW - Assisted reproduction
KW - First trimester
KW - Quadruplet pregnancy
KW - Twin-to-twin transfusion syndrome
KW - Ultrasound
UR - http://www.scopus.com/inward/record.url?scp=0036974324&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036974324&partnerID=8YFLogxK
U2 - 10.1159/000065385
DO - 10.1159/000065385
M3 - Article
C2 - 12393966
AN - SCOPUS:0036974324
VL - 17
SP - 357
EP - 361
JO - Fetal Diagnosis and Therapy
JF - Fetal Diagnosis and Therapy
SN - 1015-3837
IS - 6
ER -