First-trimester prediction of small-for-gestational age neonates incorporating fetal Doppler parameters and maternal characteristics

Viola Seravalli; Dana M. Block-Abraham; Ozhan M. Turan; Lauren E. Doyle; Jerome N. Kopelman; Robert O. Atlas; Chuka B. Jenkins; Miriam G. Blitzer; Ahmet Baschat

doi:10.1016/j.ajog.2014.03.022

First-trimester prediction of small-for-gestational age neonates incorporating fetal Doppler parameters and maternal characteristics

Viola Seravalli, Dana M. Block-Abraham, Ozhan M. Turan, Lauren E. Doyle, Jerome N. Kopelman, Robert O. Atlas, Chuka B. Jenkins, Miriam G. Blitzer, Ahmet Baschat

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Objective First-trimester screening for subsequent delivery of a small-for-gestational-age (SGA) infant typically focuses on maternal risk factors and uterine artery (UtA) Doppler. Our aim is to test if incorporation of fetal umbilical artery (UA) and ductus venosus (DV) Doppler improves SGA prediction. Study Design Prospective screening study of singletons at 11-14 weeks. Maternal characteristics, serum concentrations of pregnancy-associated plasma protein-A (PAPP-A) and free β-human chorionic gonadotropin are ascertained and UtA Doppler, UA, and DV Doppler studies are performed. These parameters are tested for their ability to predict subsequent delivery of a SGA infant. Results Among 2267 enrolled women, 191 (8.4%) deliver an SGA infant. At univariate analysis women with SGA neonates are younger, more frequently African-American (AA), nulliparous, more likely to smoke, have lower PAPP-A and free β-human chorionic gonadotropin levels. They have a higher incidence of UtA Doppler bilateral notching, higher mean UtA Doppler-pulsatility index z-scores (P

Original language	English (US)
Journal	American Journal of Obstetrics and Gynecology
Volume	211
Issue number	3
DOIs	https://doi.org/10.1016/j.ajog.2014.03.022
State	Published - 2014
Externally published	Yes

Keywords

Fetal Doppler
first-trimester screening
small for gestational age
umbilical artery
uterine artery

ASJC Scopus subject areas

Obstetrics and Gynecology

Access to Document

10.1016/j.ajog.2014.03.022

Cite this

Seravalli, V., Block-Abraham, D. M., Turan, O. M., Doyle, L. E., Kopelman, J. N., Atlas, R. O., Jenkins, C. B., Blitzer, M. G., & Baschat, A. (2014). First-trimester prediction of small-for-gestational age neonates incorporating fetal Doppler parameters and maternal characteristics. American Journal of Obstetrics and Gynecology, 211(3). https://doi.org/10.1016/j.ajog.2014.03.022

@article{f685aee170ba472c9a0493337c63fb98,

title = "First-trimester prediction of small-for-gestational age neonates incorporating fetal Doppler parameters and maternal characteristics",

abstract = "Objective First-trimester screening for subsequent delivery of a small-for-gestational-age (SGA) infant typically focuses on maternal risk factors and uterine artery (UtA) Doppler. Our aim is to test if incorporation of fetal umbilical artery (UA) and ductus venosus (DV) Doppler improves SGA prediction. Study Design Prospective screening study of singletons at 11-14 weeks. Maternal characteristics, serum concentrations of pregnancy-associated plasma protein-A (PAPP-A) and free β-human chorionic gonadotropin are ascertained and UtA Doppler, UA, and DV Doppler studies are performed. These parameters are tested for their ability to predict subsequent delivery of a SGA infant. Results Among 2267 enrolled women, 191 (8.4%) deliver an SGA infant. At univariate analysis women with SGA neonates are younger, more frequently African-American (AA), nulliparous, more likely to smoke, have lower PAPP-A and free β-human chorionic gonadotropin levels. They have a higher incidence of UtA Doppler bilateral notching, higher mean UtA Doppler-pulsatility index z-scores (P ",

keywords = "Fetal Doppler, first-trimester screening, small for gestational age, umbilical artery, uterine artery",

author = "Viola Seravalli and Block-Abraham, {Dana M.} and Turan, {Ozhan M.} and Doyle, {Lauren E.} and Kopelman, {Jerome N.} and Atlas, {Robert O.} and Jenkins, {Chuka B.} and Blitzer, {Miriam G.} and Ahmet Baschat",

year = "2014",

doi = "10.1016/j.ajog.2014.03.022",

language = "English (US)",

volume = "211",

journal = "American Journal of Obstetrics and Gynecology",

issn = "0002-9378",

publisher = "Mosby Inc.",

number = "3",

}

TY - JOUR

T1 - First-trimester prediction of small-for-gestational age neonates incorporating fetal Doppler parameters and maternal characteristics

AU - Seravalli, Viola

AU - Block-Abraham, Dana M.

AU - Turan, Ozhan M.

AU - Doyle, Lauren E.

AU - Kopelman, Jerome N.

AU - Atlas, Robert O.

AU - Jenkins, Chuka B.

AU - Blitzer, Miriam G.

AU - Baschat, Ahmet

PY - 2014

Y1 - 2014

N2 - Objective First-trimester screening for subsequent delivery of a small-for-gestational-age (SGA) infant typically focuses on maternal risk factors and uterine artery (UtA) Doppler. Our aim is to test if incorporation of fetal umbilical artery (UA) and ductus venosus (DV) Doppler improves SGA prediction. Study Design Prospective screening study of singletons at 11-14 weeks. Maternal characteristics, serum concentrations of pregnancy-associated plasma protein-A (PAPP-A) and free β-human chorionic gonadotropin are ascertained and UtA Doppler, UA, and DV Doppler studies are performed. These parameters are tested for their ability to predict subsequent delivery of a SGA infant. Results Among 2267 enrolled women, 191 (8.4%) deliver an SGA infant. At univariate analysis women with SGA neonates are younger, more frequently African-American (AA), nulliparous, more likely to smoke, have lower PAPP-A and free β-human chorionic gonadotropin levels. They have a higher incidence of UtA Doppler bilateral notching, higher mean UtA Doppler-pulsatility index z-scores (P

AB - Objective First-trimester screening for subsequent delivery of a small-for-gestational-age (SGA) infant typically focuses on maternal risk factors and uterine artery (UtA) Doppler. Our aim is to test if incorporation of fetal umbilical artery (UA) and ductus venosus (DV) Doppler improves SGA prediction. Study Design Prospective screening study of singletons at 11-14 weeks. Maternal characteristics, serum concentrations of pregnancy-associated plasma protein-A (PAPP-A) and free β-human chorionic gonadotropin are ascertained and UtA Doppler, UA, and DV Doppler studies are performed. These parameters are tested for their ability to predict subsequent delivery of a SGA infant. Results Among 2267 enrolled women, 191 (8.4%) deliver an SGA infant. At univariate analysis women with SGA neonates are younger, more frequently African-American (AA), nulliparous, more likely to smoke, have lower PAPP-A and free β-human chorionic gonadotropin levels. They have a higher incidence of UtA Doppler bilateral notching, higher mean UtA Doppler-pulsatility index z-scores (P

KW - Fetal Doppler

KW - first-trimester screening

KW - small for gestational age

KW - umbilical artery

KW - uterine artery

UR - http://www.scopus.com/inward/record.url?scp=84906944021&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84906944021&partnerID=8YFLogxK

U2 - 10.1016/j.ajog.2014.03.022

DO - 10.1016/j.ajog.2014.03.022

M3 - Article

C2 - 24631442

SN - 0002-9378

VL - 211

JO - American Journal of Obstetrics and Gynecology

JF - American Journal of Obstetrics and Gynecology

IS - 3

ER -

First-trimester prediction of small-for-gestational age neonates incorporating fetal Doppler parameters and maternal characteristics

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this