First-trimester 3D power Doppler of the uteroplacental circulation space and fetal growth restriction

Mara Rosner, Pe'Er Dar, Laura L. Reimers, Thomas McAndrew, Juliana Gebb

Research output: Contribution to journalArticle

Abstract

Objective The objective of the study was to compare the 3-dimensional power Doppler (3DPD) of the uteroplacental circulation space in the first trimester between women who subsequently deliver growth-restricted vs normally grown neonates. Study Design This was a prospective observational study of singleton pregnancies at 11-14 weeks' gestation. The 3DPD indices, vascularization index, flow index, and vascularization flow index were determined on a uteroplacental circulation space sphere biopsy with the virtual organ computer-aided analysis program. Growth restriction was defined as a birthweight less than the 10th percentile for gestational age and was evaluated using both population-based and customized birth curves. Results Five hundred seventy-seven women were enrolled. Five hundred twenty-six were eligible for analysis using population centiles, and 497 were available for evaluation using customized centiles. There was no difference in the first-trimester 3DPD indices between patients with growth-restricted and normally grown neonates using either curve. Conclusion Three-dimensional power Doppler indices of the uteroplacental circulation space in the first trimester are similar between neonates who develop growth restriction and those who will grow normally.

Original languageEnglish (US)
Pages (from-to)521.e1-521.e8
JournalAmerican Journal of Obstetrics and Gynecology
Volume211
Issue number5
DOIs
StatePublished - Nov 1 2014
Externally publishedYes

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Placental Circulation
First Pregnancy Trimester
Fetal Development
Newborn Infant
Growth
Pregnancy
Population
Gestational Age
Observational Studies
Parturition
Prospective Studies
Biopsy

Keywords

  • Doppler
  • fetal growth restriction
  • placenta

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

First-trimester 3D power Doppler of the uteroplacental circulation space and fetal growth restriction. / Rosner, Mara; Dar, Pe'Er; Reimers, Laura L.; McAndrew, Thomas; Gebb, Juliana.

In: American Journal of Obstetrics and Gynecology, Vol. 211, No. 5, 01.11.2014, p. 521.e1-521.e8.

Research output: Contribution to journalArticle

Rosner, Mara ; Dar, Pe'Er ; Reimers, Laura L. ; McAndrew, Thomas ; Gebb, Juliana. / First-trimester 3D power Doppler of the uteroplacental circulation space and fetal growth restriction. In: American Journal of Obstetrics and Gynecology. 2014 ; Vol. 211, No. 5. pp. 521.e1-521.e8.
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