Firefly luciferase as a tool in molecular and cell biology

Stephen J. Gould, Suresh Subramani

Research output: Contribution to journalReview articlepeer-review

267 Scopus citations


The unique properties of firefly luciferase and the cloning of the gene for this enzyme have spawned a number of novel applications of this protein. We summarize a few of these applications including its use as a reporter gene, as a model for the study of protein import into peroxisomes, and as a component of a heterologous gene expression system.

Original languageEnglish (US)
Pages (from-to)5-13
Number of pages9
JournalAnalytical biochemistry
Issue number1
StatePublished - Nov 15 1988
Externally publishedYes

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology


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