Fibers in the condensed chromatin of thin-sectioned nuclei of five different tissues have been measured by techniques designed to generate random data, and the measurements have been analysed by statistical methods. Individual measurements varied widely for each sample of fibers. In each case, however, chromatin fibers significantly thicker in mean diameter than the 80-100 Å diameter commonly reported for sectioned chromatin were found. We conclude from these and previous observations of sectioned chromatin that the unit fibers in chromatin of a wide variety of cell types are significantly different than 80-100 Å in diameter. Apparently no one diameter can be considered to characterize the chromatin of eukaryotic nuclei.
ASJC Scopus subject areas
- Cell Biology