Fine structure of fibers in thin sections of condensed chromatin

B. R. Zirkin, Sun Kee Kim

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Fibers in the condensed chromatin of thin-sectioned nuclei of five different tissues have been measured by techniques designed to generate random data, and the measurements have been analysed by statistical methods. Individual measurements varied widely for each sample of fibers. In each case, however, chromatin fibers significantly thicker in mean diameter than the 80-100 Å diameter commonly reported for sectioned chromatin were found. We conclude from these and previous observations of sectioned chromatin that the unit fibers in chromatin of a wide variety of cell types are significantly different than 80-100 Å in diameter. Apparently no one diameter can be considered to characterize the chromatin of eukaryotic nuclei.

Original languageEnglish (US)
Pages (from-to)490-496
Number of pages7
JournalExperimental cell research
Issue number2
StatePublished - Dec 1972
Externally publishedYes

ASJC Scopus subject areas

  • Cell Biology


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