Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1

Dylan M. Glubb, Mel J. Maranian, Kyriaki Michailidou, Karen A. Pooley, Kerstin B. Meyer, Siddhartha Kar, Saskia Carlebur, Martin O'Reilly, Joshua A. Betts, Kristine M. Hillman, Susanne Kaufmann, Jonathan Beesley, Sander Canisius, John L. Hopper, Melissa C. Southey, Helen Tsimiklis, Carmel Apicella, Marjanka K. Schmidt, Annegien Broeks, Frans B. HogervorstC. Ellen Van Der Schoot, Kenneth Muir, Artitaya Lophatananon, Sarah Stewart-Brown, Pornthep Siriwanarangsan, Peter A. Fasching, Matthias Ruebner, Arif B. Ekici, Matthias W. Beckmann, Julian Peto, Isabel Dos-Santos-Silva, Olivia Fletcher, Nichola Johnson, Paul D.P. Pharoah, Manjeet K. Bolla, Qin Wang, Joe Dennis, Elinor J. Sawyer, Ian Tomlinson, Michael J. Kerin, Nicola Miller, Barbara Burwinkel, Frederik Marme, Rongxi Yang, Harald Surowy, Pascal Guénel, Thérèse Truong, Florence Menegaux, Marie Sanchez, Stig E. Bojesen, Børge G. Nordestgaard, Sune F. Nielsen, Henrik Flyger, Anna González-Neira, Javier Benitez, M. Pilar Zamora, Jose Ignacio Arias Perez, Hoda Anton-Culver, Susan L. Neuhausen, Hermann Brenner, Aida Karina Dieffenbach, Volker Arndt, Christa Stegmaier, Alfons Meindl, Rita K. Schmutzler, Hiltrud Brauch, Yon Dschun Ko, Thomas Brüning, Heli Nevanlinna, Taru A. Muranen, Kristiina Aittomäki, Carl Blomqvist, Keitaro Matsuo, Hidemi Ito, Hiroji Iwata, Hideo Tanaka, Thilo Dörk, Natalia V. Bogdanova, Sonja Helbig, Annika Lindblom, Sara Margolin, Arto Mannermaa, Vesa Kataja, Veli Matti Kosma, Jaana M. Hartikainen, Anna H. Wu, Chiu Chen Tseng, David Van Den Berg, Daniel O. Stram, Diether Lambrechts, Hui Zhao, Caroline Weltens, Erik Van Limbergen, Jenny Chang-Claude, Dieter Flesch-Janys, Anja Rudolph, Petra Seibold, Paolo Radice, Paolo Peterlongo, Monica Barile, Fabio Capra, Fergus J. Couch, Janet E. Olson, Emily Hallberg, Celine Vachon, Graham G. Giles, Roger L. Milne, Catriona McLean, Christopher A. Haiman, Brian E. Henderson, Fredrick Schumacher, Loic Le Marchand, Jacques Simard, Mark S. Goldberg, France Labrèche, Martine Dumont, Soo Hwang Teo, Cheng Har Yip, Mee Hoong See, Belinda Cornes, Ching Yu Cheng, M. Kamran Ikram, Vessela Kristensen, Wei Zheng, Sandra L. Halverson, Martha Shrubsole, Jirong Long, Robert Winqvist, Katri Pylkäs, Arja Jukkola-Vuorinen, Saila Kauppila, Irene L. Andrulis, Julia A. Knight, Gord Glendon, Sandrine Tchatchou, Peter Devilee, Robert A.E.M. Tollenaar, Caroline Seynaeve, Christi J. Van Asperen, Montserrat García-Closas, Jonine Figueroa, Stephen J. Chanock, Jolanta Lissowska, Kamila Czene, Daniel Klevebring, Hatef Darabi, Mikael Eriksson, Maartje J. Hooning, Antoinette Hollestelle, John W.M. Martens, J. Margriet Collée, Per Hall, Jingmei Li, Keith Humphreys, Xiao Ou Shu, Wei Lu, Yu Tang Gao, Hui Cai, Angela Cox, Simon S. Cross, Malcolm W.R. Reed, William Blot, Lisa B. Signorello, Qiuyin Cai, Mitul Shah, Maya Ghoussaini, Daehee Kang, Ji Yeob Choi, Sue K. Park, Dong Young Noh, Mikael Hartman, Hui Miao, Wei Yen Lim, Anthony Tang, Ute Hamann, Diana Torres, Anna Jakubowska, Jan Lubinski, Katarzyna Jaworska, Katarzyna Durda, Suleeporn Sangrajrang, Valerie Gaborieau, Paul Brennan, James McKay, Curtis Olswold, Susan Slager, Amanda E. Toland, Drakoulis Yannoukakos, Chen Yang Shen, Pei Ei Wu, Jyh Cherng Yu, Ming Feng Hou, Anthony Swerdlow, Alan Ashworth, Nick Orr, Michael Jones, Guillermo Pita, M. Rosario Alonso, Nuria Álvarez, Daniel Herrero, Daniel C. Tessier, Daniel Vincent, Francois Bacot, Craig Luccarini, Caroline Baynes, Shahana Ahmed, Catherine S. Healey, Melissa A. Brown, Bruce A.J. Ponder, Georgia Chenevix-Trench, Deborah J. Thompson, Stacey L. Edwards, Douglas F. Easton, Alison M. Dunning, Juliet D. French

School of Medicine

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Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1

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Medicine & Life Sciences