Fine needle aspiration cytology of hepatic metastasis from a meningeal hemangiopericytoma: A case report

Hasan Ghaffar, Anil Parwani, Dorothy L. Rosenthal

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND: Hemangiopericytomas (HPCs) are rare spindle cell tumors, constituting 2.5% of soft tissue neoplasms. Few reports have addressed the fine needle aspiration (FNA) cytology of HPC. CASE: We describe the FNA biopsy (FNAB) findings in a 44-year-old patient with a previously resected meningeal hemangiopericytoma. The patient underwent ultrasound-guided FNAB of a 16.0-cm, radiographically heterogeneous density in the liver. The FNA smear showed crowded, ovoid to spindle-shaped cells with poorly defined, scant cytoplasm. The neoplastic cells were positive for CD34 and negative for CD31, factor VIII, glial fibrillary acid protein and cytokeratin AE1/AE3, supporting a diagnosis of HPC and compatible with metastasis from the patient's cerebral tumor. CONCLUSION: This case documents the role of FNA cytology in confirming HPC.

Original languageEnglish (US)
Pages (from-to)281-286
Number of pages6
JournalActa cytologica
Volume47
Issue number2
DOIs
StatePublished - 2003

Keywords

  • Aspiration biopsy
  • Hemangiopericytoma
  • Liver cancer
  • Meningeal neoplasms
  • Metastasis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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