Fine needle aspiration biopsy of deep cerebrum. A comparison of normal and neoplastic morphology

B. J. Crain, S. H. Bigner, W. W. Johnston

Research output: Contribution to journalArticle

Abstract

Fine needle aspirates of deep white matter, basal ganglia and thalamus from necropsies of three neurologically normal men were compared with two aspirates of cerebral infarcts and with eight aspirates from neoplasms that occurred in the deep cerebrum. Normal white matter contained oligodendroglia with small, dark, round nuclei and atrocytes with larger, bland, oval nuclei and occasional cytoplasmic extensions. Basal ganglia and thalamus contained, in addition, numerous neurons with large nuclei and prominent nucleoli. Recognition of these normal components of the deep cerebral structures is necessary to avoid erroneous diagnoses of neoplasia.

Original languageEnglish (US)
Pages (from-to)772-778
Number of pages7
JournalActa cytologica
Volume26
Issue number6
StatePublished - Dec 1 1982

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ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

Cite this

Crain, B. J., Bigner, S. H., & Johnston, W. W. (1982). Fine needle aspiration biopsy of deep cerebrum. A comparison of normal and neoplastic morphology. Acta cytologica, 26(6), 772-778.