Finding novelty with uncertainty

Jacob C. Reinhold, Yufan He, Shizhong Han, Yunqiang Chen, Dashan Gao, Junghoon Lee, Jerry L. Prince, Aaron Carass

Research output: Contribution to journalArticlepeer-review

Abstract

Medical images are often used to detect and characterize pathology and disease; however, automatically identifying and segmenting pathology in medical images is challenging because the appearance of pathology across diseases varies widely. To address this challenge, we propose a Bayesian deep learning method that learns to translate healthy computed tomography images to magnetic resonance images and simultaneously calculates voxel-wise uncertainty. Since high uncertainty occurs in pathological regions of the image, this uncertainty can be used for unsupervised anomaly segmentation. We show encouraging experimental results on an unsupervised anomaly segmentation task by combining two types of uncertainty into a novel quantity we call scibilic uncertainty.

Original languageEnglish (US)
JournalUnknown Journal
StatePublished - Feb 11 2020

Keywords

  • Image translation
  • Uncertainty quantification
  • Unsupervised anomaly segmentation

ASJC Scopus subject areas

  • General

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