TY - JOUR
T1 - Filtration of protein colloids by fibrous membranes
T2 - A mechanistic investigation using packed bed filtration approach
AU - Ma, Jing
AU - Wang, Yifei
AU - Zhang, Xiaolei
AU - Huang, Haiou
N1 - Funding Information:
This work was financially supported by the National Natural Science Foundation of China (Grant No. 21447004 ) and the Special Fund for State Joint Key Laboratory of Environmental Simulation and Pollution Control of China (Grant No. 2070403GK ).
Publisher Copyright:
© 2016 Elsevier B.V.
PY - 2016/8/5
Y1 - 2016/8/5
N2 - This research aimed to use packed bed filtration as a novel approach to investigate fibrous membrane filtration of aqueous particles, a novel environmental application of fibrous materials and a new frontier for engineering colloidal science. For this purpose, bovine serum albumin (BSA) was filtered through a pre-characterized glass bead column to determine attachment efficiencies (α) of BSA onto glass beads. Subsequently, BSA was filtered through a glass-fiber membrane possessing similar surface elemental compositions as the glass beads. By simulating the glass fiber membrane as a packing of spherical glass particles with a diameter equivalent to fiber diameter, α values pertinent to BSA-glass fiber attachment were calculated using the clean bed efficiency model. A side-by-side comparison of the α values show that membrane filtration exhibited greater α values than column filtration, the α values calculated for membrane filtration were always about 1.5 times of those determined under similar conditions in column filtration. However, α values for the two systems varied with solution chemistry in similar trends and the maximal α values for both systems were both found at the isoelectric point of BSA (pHIEP = 4.78). This finding implies that fibrous membrane filtration may be studied using classical packed bed filtration theories.
AB - This research aimed to use packed bed filtration as a novel approach to investigate fibrous membrane filtration of aqueous particles, a novel environmental application of fibrous materials and a new frontier for engineering colloidal science. For this purpose, bovine serum albumin (BSA) was filtered through a pre-characterized glass bead column to determine attachment efficiencies (α) of BSA onto glass beads. Subsequently, BSA was filtered through a glass-fiber membrane possessing similar surface elemental compositions as the glass beads. By simulating the glass fiber membrane as a packing of spherical glass particles with a diameter equivalent to fiber diameter, α values pertinent to BSA-glass fiber attachment were calculated using the clean bed efficiency model. A side-by-side comparison of the α values show that membrane filtration exhibited greater α values than column filtration, the α values calculated for membrane filtration were always about 1.5 times of those determined under similar conditions in column filtration. However, α values for the two systems varied with solution chemistry in similar trends and the maximal α values for both systems were both found at the isoelectric point of BSA (pHIEP = 4.78). This finding implies that fibrous membrane filtration may be studied using classical packed bed filtration theories.
KW - Bovine serum albumin
KW - Depth filtration
KW - Fibrous membranes
KW - Multi-layer adsorption
KW - Physic-chemical interactions
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U2 - 10.1016/j.colsurfa.2016.05.005
DO - 10.1016/j.colsurfa.2016.05.005
M3 - Article
AN - SCOPUS:84966712937
SN - 0927-7757
VL - 502
SP - 44
EP - 53
JO - Colloids and Surfaces A: Physicochemical and Engineering Aspects
JF - Colloids and Surfaces A: Physicochemical and Engineering Aspects
ER -