Field evaluation of a simplified unit-dose syringe for administration of measles vaccine

Neal A Halsey, Susan Berry, Peter Carrasco, Ciro De Quadros, Josefina Martinez, Juan José Arroyo, Victor Daniel España, Eugenio Duarte, Edgar Huertas, José Ramiro Cruz, Dean Sienko

Research output: Contribution to journalArticle

Abstract

Ezeject is a plungerless syringe prefilled with lyophilized measles vaccine. Ezeject syringes were compared with standard 3-cc syringes and to-dose measles vaccine vials in the vaccination of 884 Guatemalan infants 8-23 months of age. Vaccination was performed by experienced vaccinators and by individuals without prior vaccination experience who received 2.5-3 hours of training. The overall seroconversion rate following administration was 96010, regardless of the type of syringe used or of the experience of the vaccinator. No significant adverse events were observed in children vaccinated with the new syringes. Although incomplete emptying was noted in 87% of the Ezeject syringes used, this had no effect on the serologic response to measles vaccine. Aspiration for detection of blood before injection of the vaccine was performed significantly (P

Original languageEnglish (US)
Pages (from-to)S631-S638
JournalClinical Infectious Diseases
Volume11
DOIs
StatePublished - 1989

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Measles Vaccine
Syringes
Vaccination
Vaccines
Injections

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)

Cite this

Field evaluation of a simplified unit-dose syringe for administration of measles vaccine. / Halsey, Neal A; Berry, Susan; Carrasco, Peter; Quadros, Ciro De; Martinez, Josefina; Arroyo, Juan José; España, Victor Daniel; Duarte, Eugenio; Huertas, Edgar; Cruz, José Ramiro; Sienko, Dean.

In: Clinical Infectious Diseases, Vol. 11, 1989, p. S631-S638.

Research output: Contribution to journalArticle

Halsey, NA, Berry, S, Carrasco, P, Quadros, CD, Martinez, J, Arroyo, JJ, España, VD, Duarte, E, Huertas, E, Cruz, JR & Sienko, D 1989, 'Field evaluation of a simplified unit-dose syringe for administration of measles vaccine', Clinical Infectious Diseases, vol. 11, pp. S631-S638. https://doi.org/10.1093/clinids/11.Supplement_3.S631
Halsey, Neal A ; Berry, Susan ; Carrasco, Peter ; Quadros, Ciro De ; Martinez, Josefina ; Arroyo, Juan José ; España, Victor Daniel ; Duarte, Eugenio ; Huertas, Edgar ; Cruz, José Ramiro ; Sienko, Dean. / Field evaluation of a simplified unit-dose syringe for administration of measles vaccine. In: Clinical Infectious Diseases. 1989 ; Vol. 11. pp. S631-S638.
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