@article{07c1378429f949eea02944d604650d81,
title = "Fidelity and adherence to a liquefied petroleum gas stove and fuel intervention during gestation: The multi-country household air pollution intervention network (hapin) randomized controlled trial",
abstract = "Background: Clean cookstove interventions can theoretically reduce exposure to household air pollution and benefit health, but this requires near-exclusive use of these types of stoves with the simultaneous disuse of traditional stoves. Previous cookstove trials have reported low adoption of new stoves and/or extensive continued traditional stove use. Methods: The Household Air Pollution Intervention Network (HAPIN) trial randomized 3195 pregnant women in Guatemala, India, Peru, and Rwanda to either a liquefied petroleum gas (LPG) stove and fuel intervention (n = 1590) or to a control (n = 1605). The intervention consisted of an LPG stove and two initial cylinders of LPG, free fuel refills delivered to the home, and regular behavioral messaging. We assessed intervention fidelity (delivery of the intervention as intended) and adherence (intervention use) through to the end of gestation, as relevant to the first primary health outcome of the trial: infant birth weight. Fidelity and adherence were evaluated using stove and fuel delivery records, questionnaires, visual observations, and temperature-logging stove use monitors (SUMs). Results: 1585 women received the intervention at a median (interquartile range) of 8.0 (5.0–15.0) days post-randomization and had a gestational age of 17.9 (15.4–20.6) weeks. Over 96% reported cooking exclusively with LPG at two follow-up visits during pregnancy. Less than 4% reported ever running out of LPG. Complete abandonment of traditional stove cooking was observed in over 67% of the intervention households. Of the intervention households, 31.4% removed their traditional stoves upon receipt of the intervention; among those who retained traditional stoves, the majority did not use them: traditional stove use was detected via SUMs on a median (interquartile range) of 0.0% (0.0%, 1.6%) of follow-up days (median follow-up = 134 days). Conclusions: The fidelity of the HAPIN intervention, as measured by stove installation, timely ongoing fuel deliveries, and behavioral reinforcement as needed, was high. Exclusive use of the intervention during pregnancy was also high.",
keywords = "Adherence, Cookstoves, Fidelity, Intervention, LPG, Randomized controlled trial",
author = "{HAPIN investigators} and Quinn, {Ashlinn K.} and Williams, {Kendra N.} and Thompson, {Lisa M.} and Harvey, {Steven A.} and Ricardo Piedrahita and Jiantong Wang and Casey Quinn and Ajay Pillarisetti and McCracken, {John P.} and Rosenthal, {Joshua P.} and Kirby, {Miles A.} and Artiga, {Anait{\'e} Diaz} and Gurusamy Thangavel and Ghislaine Rosa and Miranda, {J. Jaime} and William Checkley and Peel, {Jennifer L.} and Clasen, {Thomas F.}",
note = "Funding Information: The HAPIN trial is funded by the US National Institutes of Health (cooperative agreement 1UM1HL134590; MPIs: Checkley, Clasen, and Peel) in collaboration with the Bill & Melinda Gates Foundation (OPP1131279). Kendra N. Williams was additionally supported by the NIH Fogarty International Center, NINDS, NIMH, NHBLI, and NIEHS under NIH Research Training Grant D43TW009340, and by the NIH/NHLBI under Award Number T32HL007534. The findings and conclusions in this report are those of the authors, and do not necessarily represent the official position of the US National Institutes of Health or the Department of Health and Human Services. This work was supported, in whole or in part, by the Bill & Melinda Gates Foundation (OPP1131279). Under the grant conditions of the Foundation, a Creative Commons Attribution 4.0 generic license has already been assigned to the author accepted manuscript version that might arise from this submission. Funding Information: Acknowledgments: The authors wish to thank trial participants and research staff for their invaluable contributions to this work. We particularly recognize the efforts of the following staff, who were responsible for stove delivery, gas delivery, stove use monitoring, and behavioral reinforcement. Guatemala: Roberto Otsoy, Alexander Ramirez, Francisco Ramirez, Misael Ramirez, Wagner Sanchez, Rosa Torres, and Carla Trinidad. India: Durairaj Natesan, Rengaraj Ramasamy, Meenakshi Sundarem Gopal Krishna, Priyakumar Natarajan, Sylesh Loganathan, Vinayagamurthy Agoram, Sivavadivel Subramaniyan, Velumani Manoharan, Ajith Velayudham, Shankar Murugesan, Suresh Krishna, Maruthamuthu Arunachalam, Thangadurai Ramasamy, Sakthivel Rajendhiran, Jayaseelan Kathirvel, and Aravind Sekar. Rwanda: Zoe Sakas, Bernard Muyaliyani, Florien Ndagiimana, Eric Tuyishimire, Martin Sherman, Prosper Twagirayezu, Tony Rugiara, Cedrick Mugisha, Raymond Nza-bandora, Eddy Frank Muhirwe, and Michel Kamali. Peru: Edison Cueva Chambi, Wilson Mendoza Inguilla, Leonora Condori Mamani, Hayde{\'e} Catacora Pari, Uriel Flores Palomino, Blenda Abarca Diaz, Jesus Reyes, David Vilca Ticona, and Suhey Vilca Mamani. A multidisciplinary, independent Data and Safety Monitoring Board (DSMB), appointed by the National Heart, Lung, and Blood Institute (NHLBI), monitors the quality of the data and protects the safety of patients enrolled in the HAPIN trial. NHLBI DSMB: Nancy R Cook, Stephen Hecht, Catherine Karr, Joseph Millum, Nalini Sathiakumar (Chair), Paul K Whelton, and Gail G Weinmann (Executive Secretary). Program Coordination: Gail Rodgers, Bill & Melinda Gates Foundation; Claudia L Thompson, National Institute of Environmental Health Science; Mark J. Parascandola, National Cancer Institute; Danuta M Krotoski and Marion Koso-Thomas, Eunice Kennedy Shriver National Institute of Child Health and Human Development; Joshua P Rosenthal, Fogarty International Center; Conception R Nierras, NIH Office of Strategic Coordination Common Fund; and Katie Kavounis, Dong-Yun Kim, Antonello Punturieri, and Barry S Schmetter, NHLBI. Funding Information: Funding: The HAPIN trial is funded by the US National Institutes of Health (cooperative agreement 1UM1HL134590; MPIs: Checkley, Clasen, and Peel) in collaboration with the Bill & Melinda Gates Foundation (OPP1131279). Kendra N. Williams was additionally supported by the NIH Fogarty International Center, NINDS, NIMH, NHBLI, and NIEHS under NIH Research Training Grant D43TW009340, and by the NIH/NHLBI under Award Number T32HL007534. The findings and conclusions in this report are those of the authors, and do not necessarily represent the official position of the US National Institutes of Health or the Department of Health and Human Services. This work was supported, in whole or in part, by the Bill & Melinda Gates Foundation (OPP1131279). Under the grant conditions of the Foundation, a Creative Commons Attribution 4.0 generic license has already been assigned to the author accepted manuscript version that might arise from this submission. Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",
year = "2021",
month = dec,
day = "1",
doi = "10.3390/ijerph182312592",
language = "English (US)",
volume = "18",
journal = "International Journal of Environmental Research and Public Health",
issn = "1661-7827",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "23",
}