Fibrous myopathy. A rheumatic complication of drug abuse.

K. R. Johnson, W. A. Hsueh, S. M. Glusman, F. C. Arnett

Research output: Contribution to journalArticle

Abstract

A progressive fibrous myopathy may result from chronic intramuscular drug abuse. This complication may mimic other rheumatic disorders and early recognition may prevent disability. The patient described here presented with fixed flexion and extension contracture of hips and knees, respectively, after abusing meperidine and other agents for 3 years. Soft tissues of thighs and buttocks were "wood hard," EMG showed absence of action potentials in affected muscles, and biopsy revealed extensive replacement of muscle with dense, acellular fibrous tissue. Possible mechanisms are discussed.

Original languageEnglish (US)
Pages (from-to)923-926
Number of pages4
JournalArthritis and Rheumatism
Volume19
Issue number5
StatePublished - Sep 1976

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Muscular Diseases
Substance-Related Disorders
Hip Contracture
Muscles
Meperidine
Buttocks
Thigh
Action Potentials
Knee
Biopsy

ASJC Scopus subject areas

  • Immunology
  • Rheumatology

Cite this

Johnson, K. R., Hsueh, W. A., Glusman, S. M., & Arnett, F. C. (1976). Fibrous myopathy. A rheumatic complication of drug abuse. Arthritis and Rheumatism, 19(5), 923-926.

Fibrous myopathy. A rheumatic complication of drug abuse. / Johnson, K. R.; Hsueh, W. A.; Glusman, S. M.; Arnett, F. C.

In: Arthritis and Rheumatism, Vol. 19, No. 5, 09.1976, p. 923-926.

Research output: Contribution to journalArticle

Johnson, KR, Hsueh, WA, Glusman, SM & Arnett, FC 1976, 'Fibrous myopathy. A rheumatic complication of drug abuse.', Arthritis and Rheumatism, vol. 19, no. 5, pp. 923-926.
Johnson KR, Hsueh WA, Glusman SM, Arnett FC. Fibrous myopathy. A rheumatic complication of drug abuse. Arthritis and Rheumatism. 1976 Sep;19(5):923-926.
Johnson, K. R. ; Hsueh, W. A. ; Glusman, S. M. ; Arnett, F. C. / Fibrous myopathy. A rheumatic complication of drug abuse. In: Arthritis and Rheumatism. 1976 ; Vol. 19, No. 5. pp. 923-926.
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