Fibrosis and atrophy in the renal allograft: Interim report and new directions

Lorraine C. Racusen, Kim Solez, Robert Colvin

Research output: Contribution to journalArticlepeer-review

58 Scopus citations

Abstract

The topic of chronic allograft nephropathy/chronic rejection is reviewed, with focus on fibrosing/sclerosing changes and late loss of function in renal allografts. Discussion includes a review of the problem, pathological and clinical findings, and new directions. Emphasis is placed on definition of specific diagnostic entities in these allografts, and identification of ongoing/active processes in this setting that might be amenable to direct intervention. A schema for categorizing these cases is proposed.

Original languageEnglish (US)
Pages (from-to)203-206
Number of pages4
JournalAmerican Journal of Transplantation
Volume2
Issue number3
DOIs
StatePublished - Mar 2002

Keywords

  • Allograft nephropathy
  • Chronic rejection
  • Kidney transplant

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation
  • Pharmacology (medical)

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