Fetal outcome among pregnancies in natural family planning acceptors: An international cohort study

Joe Leigh Simpson, Ronald H. Gray, John T. Queenan, Robert T. Kambic, Alfredo Pérez, Patricio Mena, Michele Barbato, Francisco Pardo, Guillermo Tagliabue, Adenike Bitto, Wilma Stevenson

Research output: Contribution to journalArticle

Abstract

This international, multicenter, prospective cohort study examines the outcome of pregnancies associated with aging gametes. Comparing pregnancies conceived at or near the peak mucus phase with those occurring before or after the peak provides a means of evaluating the effect of aging gametes. The outcome criteria are (1) rates of spontaneous abortion, (2) low birth weight, and (3) congenital malformations. Preliminary analysis shows a trend toward increased spontaneous abortion with aging gametes in certain subsets (women with prior pregnancy losses) but no effect on birth weight. Too few method failures have yet been studied to make a definitive statement on congenital malformations.

Original languageEnglish (US)
Pages (from-to)1981-1982
Number of pages2
JournalAmerican journal of obstetrics and gynecology
Volume165
Issue number6
DOIs
StatePublished - Jan 1 1991

Keywords

  • Natural family planning
  • aging gametes
  • congenital malformations
  • fetal outcome
  • spontaneous abortion

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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    Simpson, J. L., Gray, R. H., Queenan, J. T., Kambic, R. T., Pérez, A., Mena, P., Barbato, M., Pardo, F., Tagliabue, G., Bitto, A., & Stevenson, W. (1991). Fetal outcome among pregnancies in natural family planning acceptors: An international cohort study. American journal of obstetrics and gynecology, 165(6), 1981-1982. https://doi.org/10.1016/S0002-9378(11)90557-2