Fetal magnetic resonance imaging of the brain: Technical considerations and normal brain development

Thierry A G M Huisman, Ernst Martin, Rahel Kubik-Huch, Borut Marincek

Research output: Contribution to journalArticlepeer-review

Abstract

Fetal MRI examines non-invasively the unborn fetus. Ultrafast MRI sequences effectively suppress fetal motion. Multiple case reports and studies have shown that fetal MRI is particularly helpful in the evaluation of the central nervous system. The high contrast-to-noise ratio, the high spatial resolution, the multiplanar capabilities, the large field of view and the simultaneous visualisation of fetal and maternal structures have proven to be advantageous. Fetal MRI is particularly helpful in the evaluation of the normal and pathological development of the brain. Despite the fact that no side effects have been reported or are to be expected, the use of MRI during pregnancy is still limited to the second and third trimester of pregnancy. Magnetic resonance imaging contrast media are not to be used as it passes the placenta. Ultrasound remains the primary screening modality for fetal pathology; fetal MRI can serve as an adjunct or second-line imaging modality.

Original languageEnglish (US)
Pages (from-to)1941-1951
Number of pages11
JournalEuropean Radiology
Volume12
Issue number8
StatePublished - Aug 1 2002
Externally publishedYes

Keywords

  • Brain development
  • Fetal MRI
  • Migration
  • Myelination
  • Sulcation

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

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