Femoral head perfusion and composition: MR imaging and spectroscopic evaluation of patients with systemic lupus erythematosus and at risk for avascular necrosis

Research output: Contribution to journalArticle

Abstract

PURPOSE: To measure fat content and relative marrow perfusion of the femoral head in patients at risk for avascular necrosis. MATERIALS AND METHODS: Thirteen patients with systemic lupus erythematosus (SLE) without avascular necrosis and with long-term corticosteroid treatment and 12 healthy subjects were evaluated. Hip perfusion was assessed with gadolinium-enhanced T1-weighted magnetic resonance (MR) imaging. Marrow composition in the femoral head and neck was measured with hydrogen-1 MR spectroscopy. RESULTS: Percentage fat content in the femoral head was similar between the two groups (SLE patients, 77% ± 5 [standard deviation]; healthy subjects, 78% ± 6; P = .74). Rate of enhancement of the femoral head was significantly higher in the SLE than the healthy group (11%/min ± 6 vs 6.9%/min ± 3, respectively; P = .05), was inversely related to fat content in healthy subjects (r = -.74, P = .02), and was more variable in the SLE group (r = -.53, P = .11). CONCLUSION: Perfusion of the femoral head is inversely related to marrow fat content in healthy subjects and is higher in SLE patients without hip avascular necrosis.

Original languageEnglish (US)
Pages (from-to)433-438
Number of pages6
JournalRADIOLOGY
Volume197
Issue number2
DOIs
StatePublished - Nov 1995

Keywords

  • Bone marrow, MR
  • Hip, MR
  • Hip, necrosis
  • Lupus erythematosus
  • Magnetic resonance (MR), perfusion study
  • Magnetic resonance (MR), spectroscopy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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