Feedback control in intracellular signaling pathways: Regulating chemotaxis in dictyostelium discoideum

Research output: Contribution to journalArticlepeer-review

Abstract

Positive and negative feedback loops are used throughout engineering to tradeoff between amplification and robustness. We show how the social amoebae Dictyostelium discoideum uses these same principles to aggregate during starvation, allowing it to survive difficult environmental conditions.

Original languageEnglish (US)
Pages (from-to)227-236
Number of pages10
JournalEuropean Journal of Control
Volume9
Issue number2-3
DOIs
StatePublished - 2003

Keywords

  • Amplification
  • Dictyostelium discoideum
  • Feedback
  • Robustness
  • Signal transduction

ASJC Scopus subject areas

  • Engineering(all)

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